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Repository for lectin-assisted multimodality data
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MIRAGE
Inhibitor of nuclear factor kappa-B kinase subunit beta
Summary
- UniProt ID
- O14920
- Gene Symbol
-
- IKBKB
- IKKB
- Gene ID
- 3551
- Organism
- Homo sapiens (human)
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of NF-kappaB in B cells | Homo sapiens |
| CLEC7A (Dectin-1) signaling | Homo sapiens |
| Downstream TCR signaling | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
| FCERI mediated NF-kB activation | Homo sapiens |
| IKBKB deficiency causes SCID | Homo sapiens |
| IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) | Homo sapiens |
| IKK complex recruitment mediated by RIP1 | Homo sapiens |
| IRAK1 recruits IKK complex | Homo sapiens |
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0111959 | immunodeficiency 15B | |
| DOID:0111960 | immunodeficiency 15A | |
| DOID:10283 | prostate cancer | |
| DOID:1612 | breast cancer | |
| DOID:2526 | prostate adenocarcinoma | |
| DOID:2723 | dermatitis | |
| DOID:3571 | liver cancer | |
| DOID:9352 | type 2 diabetes mellitus |
