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T-box transcription factor T

Summary

UniProt ID

O15178

Gene Symbol

TBXT
T

Organism

Homo sapiens (human)

External Links

GlyGen: O15178
PubChem: O15178
The O-GlcNAc Database: O15178
O-GlcNAcAtlas: O15178

Annotation

Keyword

3D-structure
Activator
Alternative splicing
DNA-binding
Developmental protein
Disease variant
Nucleus
Reference proteome
Transcription regulation

Gene Ontology (GO)

Displaying entries **1 - 10** of 13 in total

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2

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GO Term
positive regulation of transcription by RNA polymerase II
mesoderm formation
signal transduction
mesoderm development
anterior/posterior axis specification, embryo
negative regulation of DNA-binding transcription factor activity
cardiac muscle cell myoblast differentiation
primitive streak formation
negative regulation of transcription by RNA polymerase II
heart morphogenesis

Displaying **all 3** entries
GO Term
nucleoplasm
chromatin
nucleus

Displaying **all 5** entries
GO Term
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription factor activity
RNA polymerase II-specific DNA-binding transcription factor binding
sequence-specific double-stranded DNA binding

Annotation information from UniProt.

Sequence

MSSPGTESAGKSLQYRVDHLLSAVENELQAGSEKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSDHKEMMEEPGDSQQPGYSQWGWLLPGTSTLCPPANPHPQFGGALSLPSTHSCDRYPTLRSHRSSPYPSPYAHRNNSPTYSDNSPACLSMLQSHDNWSSLGMPAHPSMLPVSHNASPPTSSSQYPSLWSVSNGAVTPGSQAAAVSNGLGAQFFRGSPAHYTPLTHPVSAPSSSGSPLYEGAAAATDIVDSQYDAAAQGRLIASWTPVSPPSM

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 5** entries
Position	GlyTouCan ID	Source
2	G49108TO	GlyGen The O-GlcNAc Database
3	G49108TO	GlyGen The O-GlcNAc Database
6	G49108TO	GlyGen The O-GlcNAc Database
8	G49108TO	GlyGen The O-GlcNAc Database
359		GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Cardiogenesis	Homo sapiens
Epithelial-Mesenchymal Transition (EMT) during gastrulation	Homo sapiens
Formation of axial mesoderm	Homo sapiens
Formation of definitive endoderm	Homo sapiens
Formation of paraxial mesoderm	Homo sapiens
Primitive streak formation	Homo sapiens