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Protein phosphatase 1D

Summary

UniProt ID

O15297

Gene Symbol

PPM1D
WIP1

Organism

Homo sapiens (human)

External Links

GlyGen: O15297
PubChem: O15297
The Human Metabolome Database: HMDBP08794
The O-GlcNAc Database: O15297
O-GlcNAcAtlas: O15297

Annotation

Keyword

Alternative splicing
Autism spectrum disorder
Cell cycle
Cytoplasm
Disease variant
Intellectual disability
Magnesium
Manganese
Metal-binding
Nucleus
Phosphoprotein
Protein phosphatase
Reference proteome

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

1

2

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GO Term
protein dephosphorylation
negative regulation of gene expression, epigenetic
regulation of transcription initiation by RNA polymerase II
negative regulation of cell population proliferation
response to radiation
response to bacterium
G2/M transition of mitotic cell cycle
DNA methylation-dependent heterochromatin formation
DNA damage response, signal transduction by p53 class mediator
peptidyl-threonine dephosphorylation

Displaying **all 4** entries
GO Term
nucleoplasm
cytosol
nucleus
nucleolus

Displaying **all 5** entries
GO Term
myosin phosphatase activity
mitogen-activated protein kinase binding
metal ion binding
protein serine/threonine kinase activity
protein serine/threonine phosphatase activity

Annotation information from UniProt.

Sequence

MAGLYSLGVSVFSDQGGRKYMEDVTQIVVEPEPTAEEKPSPRRSLSQPLPPRPSPAALPGGEVSGKGPAVAAREARDPLPDAGASPAPSRCCRRRSSVAFFAVCDGHGGREAAQFAREHLWGFIKKQKGFTSSEPAKVCAAIRKGFLACHLAMWKKLAEWPKTMTGLPSTSGTTASVVIIRGMKMYVAHVGDSGVVLGIQDDPKDDFVRAVEVTQDHKPELPKERERIEGLGGSVMNKSGVNRVVWKRPRLTHNGPVRRSTVIDQIPFLAVARALGDLWSYDFFSGEFVVSPEPDTSVHTLDPQKHKYIILGSDGLWNMIPPQDAISMCQDQEEKKYLMGEHGQSCAKMLVNRALGRWRQRMLRADNTSAIVICISPEVDNQGNFTNEDELYLNLTDSPSYNSQETCVMTPSPCSTPPVKSLEEDPWPRVNSKDHIPALVRSNAFSENFLEVSAEIARENVQGVVIPSKDPEPLEENCAKALTLRIHDSLNNSLPIGLVPTNSTNTVMDQKNLKMSTPGQMKAQEIERTPPTNFKRTLEESNSGPLMKKHRRNGLSRSSGAQPASLPTTSQRKNSVKLTMRRRLRGQKKIGNPLLHQHRKTVCVC

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites