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E3 ubiquitin-protein ligase Midline-1

Summary

UniProt ID

O15344

Gene Symbol

MID1
FXY
RNF59
TRIM18
XPRF

Organism

Homo sapiens (human)

External Links

GlyGen: O15344
The Human Metabolome Database: HMDBP09282
The O-GlcNAc Database: O15344

Annotation

Keyword

3D-structure
Alternative splicing
Coiled coil
Cytoskeleton
Disease variant
Microtubule
Phosphoprotein
Reference proteome
Repeat
Transferase
Ubl conjugation pathway
Zinc-finger

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
microtubule cytoskeleton organization
negative regulation of microtubule depolymerization
pattern specification process
protein localization to microtubule
regulation of microtubule cytoskeleton organization
positive regulation of stress-activated MAPK cascade

Displaying **all 7** entries
GO Term
cytoplasm
Golgi apparatus
microtubule
cytosol
spindle
microtubule associated complex
centriolar satellite

Displaying **all 8** entries
GO Term
microtubule binding
enzyme binding
transferase activity
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
phosphoprotein binding
zinc ion binding

Annotation information from UniProt.

Sequence

METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHLDCTEQLP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites