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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Sialic acid-binding Ig-like lectin 5
Summary
- UniProt ID
- O15389
- Gene Symbol
-
- SIGLEC5
- CD33L2
- OBBP2
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- O15389
- The Human Metabolome Database
- HMDBP14227
Annotation
- Keyword
-
- 3D-structure
- Cell adhesion
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Lectin
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| cell adhesion |
| GO Term |
|---|
| plasma membrane |
| ficolin-1-rich granule membrane |
| secretory granule membrane |
| tertiary granule membrane |
| GO Term |
|---|
| carbohydrate binding |
| sialic acid binding |
Sequence
MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQTITIFRNGIALEILQNTSYLPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSVYSLPQLLGPSCSWEAEGLHCRCSFRARPAPSLCWRLEEKPLEGNSSQGSFKVNSSSAGPWANSSLILHGGLSSDLKVSCKAWNIYGSQSGSVLLLQGRSNLGTGVVPAALGGAGVMALLCICLCLIFFLIVKARRKQAAGRPEKMDDEDPIMGTITSGSRKKPWPDSPGDQASPPGDAPPLEEQKELHYASLSFSEMKSREPKDQEAPSTTEYSEIKTSK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 100 | N-linked (GlcNAc...) asparagine |
|
||
| 210 | N-linked (GlcNAc...) asparagine |
|
||
| 231 | N-linked (GlcNAc...) asparagine |
|
||
| 253 | N-linked (GlcNAc...) asparagine |
|
||
| 328 | N-linked (GlcNAc...) asparagine |
|
||
| 375 | N-linked (GlcNAc...) asparagine |
|
||
| 384 | N-linked (GlcNAc...) asparagine |
|
||
| 393 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G27102CT
G90093AU
G08606CV
G22310AV
G48414YA
G98205FV
G06656BE
G72797UR
G57141NR
G84452RH
G91636VS
G93019KS
G06356OH
G73455AR
G23863VK
G57818FI
G10256JP
G75698JE
G22140GZ
G50045TK
G46687AB
G75727PF
G05724UK
G21196UL
G81295CK
G98068RN
G49874UX
G80858MF
G39188ZX
G67030CA
G39943KJ
G06110VR
G90206GU
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:162 | cancer | |
| DOID:1024 | leprosy | |
| DOID:10423 | acute pericementitis | |
| DOID:1474 | aggressive periodontitis | |
| DOID:1837 | diabetic ketoacidosis | |
| DOID:824 | periodontitis | |
| DOID:9074 | systemic lupus erythematosus | |
| DOID:9119 | acute myeloid leukemia | |
| DOID:9351 | diabetes mellitus | |
| DOID:9352 | type 2 diabetes mellitus |
