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ATP-binding cassette sub-family C member 4

Summary

UniProt ID

O15439

Gene Symbol

ABCC4
MOATB
MRP4

Gene ID

10257

Organism

Homo sapiens (human)

External Links

GlyGen: O15439
PubChem: O15439
The Human Metabolome Database: HMDBP03952
RaftProt: O15439
Re-Glyco: O15439

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cell membrane
Disease variant
Glycoprotein
Lipid transport
Magnesium
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Translocase
Transmembrane helix

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
platelet dense granule membrane
nucleolus
plasma membrane
membrane
Golgi apparatus
basolateral plasma membrane
apical plasma membrane
external side of apical plasma membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 13 in total

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GO Term
xenobiotic metabolic process
xenobiotic transmembrane transport
export across plasma membrane
platelet degranulation
prostaglandin transport
urate transport
prostaglandin secretion
leukotriene transport
transport across blood-brain barrier
bile acid and bile salt transport

Displaying entries **1 - 10** of 16 in total

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GO Term
ATP binding
ABC-type xenobiotic transporter activity
ATP hydrolysis activity
ATPase-coupled transmembrane transporter activity
ABC-type transporter activity
prostaglandin transmembrane transporter activity
urate transmembrane transporter activity
ABC-type glutathione S-conjugate transporter activity
ABC-type bile acid transporter activity
efflux transmembrane transporter activity

Annotation information from UniProt.

Sequence

MLPVYQEVKPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEESAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTFCTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAIAVTALLWMEIGISCLAGMAVLIILLPLQSCFGKLFSSLRSKTATFTDARIRTMNEVITGIRIIKMYAWEKSFSNLITNLRKKEISKILRSSCLRGMNLASFFSASKIIVFVTFTTYVLLGSVITASRVFVAVTLYGAVRLTVTLFFPSAIERVSEAIVSIRRIQTFLLLDEISQRNRQLPSDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELAPSHGLVSVHGRIAYVSQQPWVFSGTLRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQILHEKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQPPVPGTPTLRNRTFSESSVWSQQSSRPSLKDGALESQDTENVPVTLSEENRSEGKVGFQAYKNYFRAGAHWIVFIFLILLNTAAQVAYVLQDWWLSYWANKQSMLNVTVNGGGNVTEKLDLNWYLGIYSGLTVATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILNRFSKDIGHLDDLLPLTFLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIIFIFLRRYFLETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAMFVIIVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDLEKEAPWEYQKRPPPAWPHEGVIIFDNVNFMYSPGGPLVLKHLTALIKSQEKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETAKQVYFKRNYPHIGHTDHMVTNTSNGQPSTLTIFETAL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites