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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Group 10 secretory phospholipase A2
Summary
- UniProt ID
- O15496
- Gene Symbol
-
- PLA2G10
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O15496
- PubChem
- O15496
- SwissLipids
- The Human Metabolome Database
- HMDBP00063
- The O-GlcNAc Database
- O15496
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cleavage on pair of basic residues
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Hydrolase
- Lysosome
- Metal-binding
- Phospholipid metabolism
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| production of molecular mediator involved in inflammatory response |
| fertilization |
| positive regulation of arachidonic acid secretion |
| negative regulation of cholesterol efflux |
| GO Term |
|---|
| acrosomal vesicle |
| extracellular region |
| extracellular space |
| lysosome |
Sequence
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 113 | N-linked (GlcNAc...) asparagine |
|
||
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Acyl chain remodelling of PC | Homo sapiens |
| Acyl chain remodelling of PE | Homo sapiens |
| Acyl chain remodelling of PG | Homo sapiens |
| Acyl chain remodelling of PI | Homo sapiens |
| Acyl chain remodelling of PS | Homo sapiens |
| Synthesis of PA | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:399 | tuberculosis | |
| DOID:4398 | pustulosis of palm and sole | |
| DOID:4766 | embryoma | |
| DOID:4851 | pilocytic astrocytoma | |
| DOID:4903 | granular cell carcinoma | |
| DOID:4929 | tubular adenocarcinoma | |
| DOID:5077 | subependymal giant cell astrocytoma | |
| DOID:5162 | arteriolosclerosis | |
| DOID:5364 | pulmonary coin lesion | |
| DOID:5419 | schizophrenia |
