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Klotho

Summary

UniProt ID

O35082

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003079
PubChem: O35082

Annotation

Keyword

Alternative splicing
Cell membrane
Glycoprotein
Glycosidase
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 12 in total

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GO Term
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
response to angiotensin
response to vitamin D
negative regulation of systemic arterial blood pressure
fibroblast growth factor receptor signaling pathway
determination of adult lifespan
response to activity
carbohydrate metabolic process
energy reserve metabolic process
calcium ion homeostasis

Displaying **all 3** entries
GO Term
apical plasma membrane
extracellular region
membrane

Displaying **all 3** entries
GO Term
beta-glucuronidase activity
fibroblast growth factor receptor binding
fibroblast growth factor binding

Annotation information from UniProt.

Sequence

MLARAPPRRPPRLVLLRLLLLHLLLLALRARCLSAEPGQGAQTWARFARAPAPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHSGAAPSDSPIVVAPSGAPSPPLSSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGRVSIALSSHWINPRRMTDYNIRECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPDFTESEKRLIRGTADFFALSFGPTLSFQLLDPNMKFRQLESPNLRQLLSWIDLEYNHPPIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIEDNGFPPLPENQPLEGTFPCDFAWGVVDNYVQVDTTLSQFTDPNVYLWDVHHSKRLIKVDGVVAKKRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNHTVLHFYRCMISELVHANITPVVALWQPAAPHQGLPHALAKHGAWENPHTALAFADYANLCFKELGHWVNLWITMNEPNTRNMTYRAGHHLLRAHALAWHLYDDKFRAAQKGKISIALQADWIEPACPFSQNDKEVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQKNNFLLPYFTEDEKKLVRGSFDFLAVSHYTTILVDWEKEDPMKYNDYLEVQEMTDITWLNSPSQVAVVPWGLRKVLNWLRFKYGDLPMYVTANGIDDDPHAEQDSLRIYYIKNYVNEALKAYVLDDINLCGYFAYSLSDRSAPKSGFYRYAANQFEPKPSMKHYRKIIDSNGFLGSGTLGRFCPEEYTVCTECGFFQTRKSLLVFISFLVFTFIISLALIFHYSKKGQRSYK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
161	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
285	N-linked (GlcNAc...) asparagine	UniProt
346	N-linked (GlcNAc...) asparagine	GlycoProtDB UniProt
609	N-linked (GlcNAc...) asparagine	UniProt
614	N-linked (GlcNAc...) asparagine	UniProt
696	N-linked (GlcNAc...) asparagine	UniProt