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Syntaxin-1A

Summary

UniProt ID

O35526

Gene Symbol

Stx1a

Gene ID

20907

Organism

Mus musculus (house mouse)

External Links

GlyGen: O35526
PubChem: O35526
The Human Metabolome Database: HMDBP14643
Re-Glyco: O35526

Annotation

Keyword

Cell membrane
Coiled coil
Cytoplasmic vesicle
Direct protein sequencing
Exocytosis
Isopeptide bond
Neurotransmitter transport
Phosphoprotein
Reference proteome
Synaptosome
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
plasma membrane
membrane
axon
nuclear membrane
neuron projection
acrosomal vesicle
synaptic vesicle
synaptic vesicle membrane
SNARE complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 15 in total

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GO Term
positive regulation of excitatory postsynaptic potential
positive regulation of neurotransmitter secretion
intracellular protein transport
positive regulation of norepinephrine secretion
insulin secretion
positive regulation of catecholamine secretion
hormone secretion
regulation of synaptic vesicle priming
synaptic vesicle exocytosis
protein sumoylation

Displaying **all 6** entries
GO Term
calcium channel inhibitor activity
SNARE binding
kinase binding
identical protein binding
SNAP receptor activity
chloride channel inhibitor activity

Annotation information from UniProt.

Sequence

MKDRTQELRTAKDSDDDDDVTVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLETSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIIIASTIGGIFG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
107			G14368ET	GlyGen
135			G72360HR	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Acetylcholine Neurotransmitter Release Cycle	Mus musculus
Dopamine Neurotransmitter Release Cycle	Mus musculus
GABA synthesis, release, reuptake and degradation	Mus musculus
Glutamate Neurotransmitter Release Cycle	Mus musculus
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Mus musculus
LGI-ADAM interactions	Mus musculus
Norepinephrine Neurotransmitter Release Cycle	Mus musculus
Other interleukin signaling	Mus musculus
Serotonin Neurotransmitter Release Cycle	Mus musculus