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MIRAGE
Cochlin

Summary
UniProt ID
O43405
Gene Symbol
  • COCH
  • COCH5B2
  • UNQ257/PRO294
Gene ID
1690
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011195
GlyGen
O43405
Re-Glyco
O43405
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Disease variant
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Hearing
  • Non-syndromic deafness
  • Reference proteome
  • Repeat
  • Signal
Gene Ontology (GO)
Displaying all 2 entries
GO Term
extracellular region
collagen-containing extracellular matrix
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
regulation of cell shape
sensory perception of sound
Displaying 1 entry
GO Term
collagen binding
Annotation information from UniProt.
Sequence
MSAAWIPALGLGVCLLLLPGPAGSEGAAPIAITCFTRGLDIRKEKADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYSSVDANGIQSQMLSRWSASFTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFYLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGWPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKPKESHAFFTREFTGLEPIVSDVIRGICRDFLESQQ
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 8 entries
Position Description PubMed ID GlyTouCan ID Source
100 N-linked (GlcNAc...) asparagine
124
128
139
140
145
221 N-linked (GlcNAc...) asparagine
257
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0110593 autosomal dominant nonsyndromic deafness 9
DOID:0111644 autosomal recessive nonsyndromic deafness 110
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025