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MIRAGE
18S rRNA (guanine-N(7))-methyltransferase

Summary
UniProt ID
O43709
Gene Symbol
  • BUD23
  • HUSSY-03
  • MERM1
  • PP3381
  • WBSCR22
Gene ID
114049
Organism
Homo sapiens (human)
PubChem
O43709
The Human Metabolome Database
HMDBP12007
The O-GlcNAc Database
O43709
Re-Glyco
O43709
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Chromatin regulator
  • Cytoplasm
  • Methyltransferase
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Ribosome biogenesis
  • S-adenosyl-L-methionine
  • Transcription regulation
  • Ubl conjugation
  • Williams-Beuren syndrome
  • rRNA processing
Gene Ontology (GO)
Displaying all 4 entries
GO Term
nucleus
nucleolus
nucleoplasm
perinuclear region of cytoplasm
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNERFPLRMSRRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
194
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Major pathway of rRNA processing in the nucleolus and cytosol Homo sapiens
rRNA modification in the nucleus and cytosol Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:1928 Williams-Beuren syndrome
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025