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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Hyaluronidase-3
Summary
- UniProt ID
- O43820
- Gene Symbol
-
- HYAL3
- LUCA3
- Organism
- Homo sapiens (human)
External Links
- PubChem
- O43820
- The Human Metabolome Database
- HMDBP11790
Annotation
- Keyword
-
- Alternative splicing
- Cell membrane
- Cytoplasmic vesicle
- Disulfide bond
- EGF-like domain
- Endoplasmic reticulum
- Endosome
- Fertilization
- Glycoprotein
- Glycosidase
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| lysosome |
| plasma membrane |
| cytoplasmic vesicle |
| endoplasmic reticulum |
| early endosome |
| sperm midpiece |
| acrosomal vesicle |
| acrosomal membrane |
| extracellular region |
| GO Term |
|---|
| hyaluronoglucuronidase activity |
| hyalurononglucosaminidase activity |
Sequence
MTTQLGPALVLGVALCLGCGQPLPQVPERPFSVLWNVPSAHCEARFGVHLPLNALGIIANRGQHFHGQNMTIFYKNQLGLYPYFGPRGTAHNGGIPQALPLDRHLALAAYQIHHSLRPGFAGPAVLDWEEWCPLWAGNWGRRRAYQAASWAWAQQVFPDLDPQEQLYKAYTGFEQAARALMEDTLRVAQALRPHGLWGFYHYPACGNGWHSMASNYTGRCHAATLARNTQLHWLWAASSALFPSIYLPPRLPPAHHQAFVRHRLEEAFRVALVGHRHPLPVLAYVRLTHRRSGRFLSQDDLVQSIGVSAALGAAGVVLWGDLSLSSSEEECWHLHDYLVDTLGPYVINVTRAAMACSHQRCHGHGRCARRDPGQMEAFLHLWPDGSLGDWKSFSCHCYWGWAGPTCQEPRPGPKEAV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CS/DS degradation | Homo sapiens |
| Hyaluronan uptake and degradation | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1380 | endometrial cancer | |
| DOID:162 | cancer | |
| DOID:1686 | glaucoma | |
| DOID:2513 | basal cell carcinoma | |
| DOID:2871 | endometrial carcinoma | |
| DOID:305 | carcinoma | |
| DOID:3070 | high grade glioma | |
| DOID:3071 | gliosarcoma | |
| DOID:3620 | central nervous system cancer | |
| DOID:3907 | lung squamous cell carcinoma |
