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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Xaa-Pro aminopeptidase 2
Summary
- UniProt ID
- O43895
- Gene Symbol
-
- XPNPEP2
- Organism
- Homo sapiens (human)
External Links
- PubChem
- O43895
- The Human Metabolome Database
- HMDBP08857
- RaftProt
- O43895
Annotation
- Keyword
-
- Aminopeptidase
- Cell membrane
- GPI-anchor
- Metal-binding
- Metalloprotease
- Reference proteome
- Signal
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| GO Term |
|---|
| extracellular region |
| plasma membrane |
| membrane |
| extracellular exosome |
| side of membrane |
| GO Term |
|---|
| metalloaminopeptidase activity |
| metal ion binding |
| aminopeptidase activity |
Sequence
MARAHWGCCPWLVLLCACAWGHTKPVDLGGQDVRNCSTNPPYLPVTVVNTTMSLTALRQQMQTQNLSAYIIPGTDAHMNEYIGQHDERRAWITGFTGSAGTAVVTMKKAAVWTDSRYWTQAERQMDCNWELHKEVGTTPIVTWLLTEIPAGGRVGFDPFLLSIDTWESYDLALQGSNRQLVSITTNLVDLVWGSERPPVPNQPIYALQEAFTGSTWQEKVSGVRSQMQKHQKVPTAVLLSALEETAWLFNLRASDIPYNPFFYSYTLLTDSSIRLFANKSRFSSETLSYLNSSCTGPMCVQIEDYSQVRDSIQAYSLGDVRIWIGTSYTMYGIYEMIPKEKLVTDTYSPVMMTKAVKNSKEQALLKASHVRDAVAVIRYLVWLEKNVPKGTVDEFSGAEIVDKFRGEEQFSSGPSFETISASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYWDGTTDITRTVHWGTPSAFQKEAYTRVLIGNIDLSRLIFPAATSGRMVEAFARRALWDAGLNYGHGTGHGIGNFLCVHEWPVGFQSNNIAMAKGMFTSIEPGYYKDGEFGIRLEDVALVVEAKTKYPGSYLTFEVVSFVPYDRNLIDVSLLSPEHLQYLNRYYQTIREKVGPELQRRQLLEEFEWLQQHTEPLAARAPDTASWASVLVVSTLAILGWSV
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Post-translational modification: synthesis of GPI-anchored proteins | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050387 | nonpapillary renal cell carcinoma | |
| DOID:0050639 | primary cutaneous amyloidosis | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:10787 | premature menopause | |
| DOID:14735 | hereditary angioedema | |
| DOID:1558 | angioedema | |
| DOID:162 | cancer | |
| DOID:2893 | cervix carcinoma | |
| DOID:3702 | cervical adenocarcinoma |
