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5-hydroxytryptamine receptor 2A

Summary

UniProt ID

O46635

Gene Symbol

5-HTR2A
HTR2A

Gene ID

403882

Organism

Canis lupus familiaris (dog)

External Links

PubChem: O46635
Re-Glyco: O46635

Annotation

Keyword

Behavior
Cell membrane
Cell projection
Cytoplasmic vesicle
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Synapse
Transmembrane helix

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
plasma membrane
axon
dendrite
cytoplasmic vesicle
presynapse
caveola
G protein-coupled serotonin receptor complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
intracellular calcium ion homeostasis
chemical synaptic transmission
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
serotonin receptor signaling pathway
phospholipase C-activating serotonin receptor signaling pathway
positive regulation of phosphatidylinositol biosynthetic process
response to xenobiotic stimulus
release of sequestered calcium ion into cytosol
positive regulation of ERK1 and ERK2 cascade

Displaying **all 7** entries
GO Term
Gq/11-coupled serotonin receptor activity
1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding
serotonin receptor activity
neurotransmitter receptor activity
identical protein binding
G protein-coupled serotonin receptor activity
serotonin binding

Annotation information from UniProt.

Sequence

MDVLFEDNAPLSPTTSSLMPSNGDPRLYGNDLNAGDANTSDAFNWTVDAENRTNLSCEGCLSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDPGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDIIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKKDAKSTDNDYSMVALGKQHSEDAPTDNINTVNEKVSCV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	Source
38	N-linked (GlcNAc...) asparagine	UniProt
44	N-linked (GlcNAc...) asparagine	UniProt
51	N-linked (GlcNAc...) asparagine	UniProt
54	N-linked (GlcNAc...) asparagine	UniProt