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MIRAGE
Integrin beta-3
Summary
- UniProt ID
- O54890
- Gene Symbol
-
- Itgb3
- Gene ID
- 16416
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003145
- GlyConnect
- GlyGen
- O54890
- PubChem
- O54890
- RaftProt
- O54890
- Re-Glyco
- O54890
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cell projection
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Integrin
- Magnesium
- Metal-binding
- Phosphoprotein
- Postsynaptic cell membrane
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| filopodium membrane |
| alphav-beta3 integrin-IGF-1-IGF1R complex |
| nucleus |
| cell-cell junction |
| melanosome |
| receptor complex |
| synapse |
| postsynaptic membrane |
| synaptic membrane |
| nucleoplasm |
Sequence
MRAQWPGQLWAALLALGALAGVVVGESNICTTRGVNSCQQCLAVSPVCAWCSDETLSQGSPRCNLKENLLKDNCAPESIEFPVSEAQILEARPLSSKGSGSSAQITQVSPQRIALRLRPDDSKIFSLQVRQVEDYPVDIYYLMDLSFSMKDDLSSIQTLGTKLASQMRKLTSNLRIGFGAFVDKPVSPYMYISPPQAIKNPCYNMKNACLPMFGYKHVLTLTDQVSRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVLPNDGHCHIGTDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVSLYQNYSELIPGTTVGVLSDDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCVGLKIGDTVSFSIEAKVRGCPQEKEQSFTIKPVGFKDSLTVQVTFDCDCACQAFAQPSSPRCNNGNGTFECGVCRCDQGWLGSMCECSEEDYRPSQQEECSPKEGQPICSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNGLLCSGRGNCECGSCVCVQPGSYGDTCEKCPTCPDACSFKKECVECKKFNRGTLHEENTCSRYCRDDIEQVKELTDTGKNAVNCTYKNEDDCVVRFQYYEDTSGRAVLYVVEEPECPKGPDILVVLLSVMGAILLIGLATLLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 345 | N-linked (GlcNAc...) asparagine |
|
||
| 396 | N-linked (GlcNAc...) asparagine | |||
| 477 | N-linked (GlcNAc...) asparagine | |||
| 584 | N-linked (GlcNAc...) asparagine |
|
||
| 679 | N-linked (GlcNAc...) asparagine |
G62765YT
G77547TA
G07755XJ
G64527OM
G06110VR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ECM proteoglycans | Mus musculus |
| Elastic fibre formation | Mus musculus |
| GRB2:SOS provides linkage to MAPK signaling for Integrins | Mus musculus |
| Integrin cell surface interactions | Mus musculus |
| Integrin signaling | Mus musculus |
| MAP2K and MAPK activation | Mus musculus |
| Molecules associated with elastic fibres | Mus musculus |
| PECAM1 interactions | Mus musculus |
| Platelet degranulation | Mus musculus |
| Signal transduction by L1 | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060691 | platelet-type bleeding disorder 16 | |
| DOID:2219 | Glanzmann's thrombasthenia |
