GlyCosmos Portal

Submissions

Nuclear factor erythroid 2-related factor 2

Summary

UniProt ID

O54968

Gene Symbol

Nfe2l2
Nrf2

Gene ID

83619

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: O54968
Re-Glyco: O54968

Annotation

Keyword

Acetylation
Activator
Alternative splicing
Cytoplasm
DNA-binding
Glycation
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

1

2

Next ›

Last »
GO Term
chromatin
nucleus
cytoplasm
plasma membrane
protein-DNA complex
nucleoplasm
Golgi apparatus
cytosol
centrosome
mediator complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 47 in total

1

2

3

4

5

Next ›

Last »
GO Term
cellular response to copper ion
cellular response to fluid shear stress
regulation of cellular response to oxidative stress
negative regulation of vascular associated smooth muscle cell migration
proteasomal ubiquitin-independent protein catabolic process
PERK-mediated unfolded protein response
aflatoxin catabolic process
cellular response to methionine
cellular response to laminar fluid shear stress
negative regulation of ferroptosis

Displaying entries **1 - 10** of 12 in total

1

2

Next ›

Last »
GO Term
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
transcription coregulator binding
DNA-binding transcription activator activity, RNA polymerase II-specific
DNA binding
DNA-binding transcription factor activity
protein domain specific binding
ubiquitin protein ligase binding
sequence-specific DNA binding
RNA polymerase II-specific DNA-binding transcription factor binding

Annotation information from UniProt.

Sequence

MMDLELPPPGLQSQQDMDLIDILWRQDIDLGVSREVFDFSQRQKDYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQTDTSGSVSYSQVAHIPKQDALYFEDCMQLLAETFPFVDDHEVSSPTFQSLALDIPSHVESSVFTTPDQAQSLDSSLETAMTDLSSIQQDMEQVWQELFSIPELQCLNTENKQQAETTTVPSPEATLTEMDSNYHFYSSIPSLEKEVDSCSPHFLHGFEDSFSSILSTDDASQLNSLDSNPTLNTDFGDEFYSAFLAEPSGGGSMPSSAAISQSLSELLGGPIEGCDLSLCKAFNQKHTEGTVEFNDSDSGISLNTSPSRASPEHSVESSIYGDPPPGFSDSEMEELDSAPGSVKQNGPKAQPTHSSGDTVQPLSPAQGHSAAVHESQCENTTKKEVPVSPGHQKVPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVDDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRKLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDTKKN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	Source
461	N-linked (Glc) (glycation) lysine	UniProt
471	N-linked (Glc) (glycation) lysine	UniProt
486	N-linked (Glc) (glycation) lysine	UniProt
498	N-linked (Glc) (glycation) arginine	UniProt
568	N-linked (Glc) (glycation) arginine	UniProt
573	N-linked (Glc) (glycation) lysine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	Rattus norvegicus
KEAP1-NFE2L2 pathway	Rattus norvegicus
Neddylation	Rattus norvegicus
Nuclear events mediated by NFE2L2	Rattus norvegicus

Disease

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:0080208	metabolic dysfunction-associated steatotic liver disease	Alliance of Genome Resources
DOID:11832	visual epilepsy	Alliance of Genome Resources
DOID:3525	middle cerebral artery infarction	Alliance of Genome Resources
DOID:3770	pulmonary fibrosis	Alliance of Genome Resources
DOID:5082	liver cirrhosis	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:8947	diabetic retinopathy	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements