Nuclear factor erythroid 2-related factor 2

Summary
UniProt ID
O54968
Gene Symbol
  • Nfe2l2
  • Nrf2
Organism
Rattus norvegicus (Norway rat)
External Links
PubChem
O54968
Annotation
Keyword
  • Acetylation
  • Activator
  • Alternative splicing
  • Cytoplasm
  • DNA-binding
  • Glycation
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Transcription regulation
  • Ubl conjugation
Gene Ontology (GO)
Sequence
MMDLELPPPGLQSQQDMDLIDILWRQDIDLGVSREVFDFSQRQKDYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQTDTSGSVSYSQVAHIPKQDALYFEDCMQLLAETFPFVDDHEVSSPTFQSLALDIPSHVESSVFTTPDQAQSLDSSLETAMTDLSSIQQDMEQVWQELFSIPELQCLNTENKQQAETTTVPSPEATLTEMDSNYHFYSSIPSLEKEVDSCSPHFLHGFEDSFSSILSTDDASQLNSLDSNPTLNTDFGDEFYSAFLAEPSGGGSMPSSAAISQSLSELLGGPIEGCDLSLCKAFNQKHTEGTVEFNDSDSGISLNTSPSRASPEHSVESSIYGDPPPGFSDSEMEELDSAPGSVKQNGPKAQPTHSSGDTVQPLSPAQGHSAAVHESQCENTTKKEVPVSPGHQKVPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVDDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRKLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDTKKN
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
461 N-linked (Glc) (glycation) lysine
471 N-linked (Glc) (glycation) lysine
486 N-linked (Glc) (glycation) lysine
498 N-linked (Glc) (glycation) arginine
568 N-linked (Glc) (glycation) arginine
573 N-linked (Glc) (glycation) lysine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 Rattus norvegicus
KEAP1-NFE2L2 pathway Rattus norvegicus
Neddylation Rattus norvegicus
Nuclear events mediated by NFE2L2 Rattus norvegicus

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024