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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3
Summary
- UniProt ID
- O60568
- Gene Symbol
-
- PLOD3
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011229
- GlyConnect
- GlyGen
- O60568
- PubChem
- O60568
- The Human Metabolome Database
- HMDBP00462
- The O-GlcNAc Database
- O60568
- RaftProt
- O60568
- O-GlcNAcAtlas
- O60568
Annotation
- Keyword
-
- 3D-structure
- Dioxygenase
- Disease variant
- Disulfide bond
- Endoplasmic reticulum
- Glycoprotein
- Glycosyltransferase
- Iron
- Manganese
- Membrane
- Metal-binding
- Multifunctional enzyme
- Reference proteome
- Secreted
- Signal
- Vitamin C
- Gene Ontology (GO)
Sequence
MTSSGPGPRFLLLLPLLLPPAASASDRPRGRDPVNPEKLLVITVATAETEGYLRFLRSAEFFNYTVRTLGLGEEWRGGDVARTVGGGQKVRWLKKEMEKYADREDMIIMFVDSYDVILAGSPTELLKKFVQSGSRLLFSAESFCWPEWGLAEQYPEVGTGKRFLNSGGFIGFATTIHQIVRQWKYKDDDDDQLFYTRLYLDPGLREKLSLNLDHKSRIFQNLNGALDEVVLKFDRNRVRIRNVAYDTLPIVVHGNGPTKLQLNYLGNYVPNGWTPEGGCGFCNQDRRTLPGGQPPPRVFLAVFVEQPTPFLPRFLQRLLLLDYPPDRVTLFLHNNEVFHEPHIADSWPQLQDHFSAVKLVGPEEALSPGEARDMAMDLCRQDPECEFYFSLDADAVLTNLQTLRILIEENRKVIAPMLSRHGKLWSNFWGALSPDEYYARSEDYVELVQRKRVGVWNVPYISQAYVIRGDTLRMELPQRDVFSGSDTDPDMAFCKSFRDKGIFLHLSNQHEFGRLLATSRYDTEHLHPDLWQIFDNPVDWKEQYIHENYSRALEGEGIVEQPCPDVYWFPLLSEQMCDELVAEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTESLFPGYHTKARAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGLDYEGGGCRFLRYDCVISSPRKGWALLHPGRLTHYHEGLPTTWGTRYIMVSFVDP
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 25 |
|
|||
| 63 | N-linked (GlcNAc...) asparagine | |||
| 65 |
|
|||
| 548 | N-linked (GlcNAc...) asparagine |
|
||
| 604 |
|
|
||
| 701 |
|
G57321FI
G83460ZZ
G25079LO
G48584BU
G70101JE
G80920RR
G14260UH
G62765YT
G64527OM
G31852PQ
G23719VF
G39188ZX
G41247ZX
G36379GD
G02815KT
G06110VR
G92275SC
G49108TO
G73027HY
G15664MX
G24528MX
G41071NU
G07755XJ
G72747WU
G59626AS
G01485JJ
G42124LM
G77547TA
G45504EY
G83633GK
G72790NZ
G95177YH
G05049YU
G85269DF
G95865ZB
G05724UK
G49955PK
G72787SB
G49874UX
G39446WN
G11314AS
G35029YA
G57776ZU
G94854LT
G57317CE
G92050GC
G28681TP
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Collagen biosynthesis and modifying enzymes | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0060058 | lymphoma | |
| DOID:0060249 | scoliosis | |
| DOID:0060735 | epidermolysis bullosa simplex Dowling-Meara type | |
| DOID:0060736 | epidermolysis bullosa simplex Ogna type | |
| DOID:0080001 | bone disease | |
| DOID:0080087 | nonsyndromic congenital nail disorder 9 | |
| DOID:0090017 | epidermolysis bullosa simplex with muscular dystrophy | |
| DOID:0111257 | gamma-glutamyl transpeptidase deficiency | |
| DOID:10003 | sensorineural hearing loss |
