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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Ficolin-1
Summary
- UniProt ID
- O70165
- Gene Symbol
-
- Fcn1
- Fcna
- Organism
- Mus musculus (house mouse)
External Links
Annotation
- Keyword
-
- Calcium
- Cell membrane
- Collagen
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Innate immunity
- Lectin
- Metal-binding
- Reference proteome
- Repeat
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| collagen trimer |
| extracellular space |
| plasma membrane |
| collagen-containing extracellular matrix |
| GO Term |
|---|
| antigen binding |
| signaling receptor binding |
| pattern recognition receptor activity |
| metal ion binding |
| carbohydrate derivative binding |
| carbohydrate binding |
Sequence
MQWPTLWAFSGLLCLCPSQALGQERGACPDVKVVGLGAQDKVVVIQSCPGFPGPPGPKGEPGSPAGRGERGFQGSPGKMGPAGSKGEPGTMGPPGVKGEKGDTGAAPSLGEKELGDTLCQRGPRSCKDLLTRGIFLTGWYTIHLPDCRPLTVLCDMDVDGGGWTVFQRRVDGSIDFFRDWDSYKRGFGNLGTEFWLGNDYLHLLTANGNQELRVDLQDFQGKGSYAKYSSFQVSEEQEKYKLTLGQFLEGTAGDSLTKHNNMSFTTHDQDNDANSMNCAALFHGAWWYHNCHQSNLNGRYLSGSHESYADGINWGTGQGHHYSYKVAEMKIRAS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 261 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Ficolins bind to repetitive carbohydrate structures on the target cell surface | Mus musculus |
| Initial triggering of complement | Mus musculus |
| Lectin pathway of complement activation | Mus musculus |
| Neutrophil degranulation | Mus musculus |
