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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Organic cation/carnitine transporter 2
Summary
- UniProt ID
- O76082
- Gene Symbol
-
- SLC22A5
- OCTN2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- O76082
- PubChem
- O76082
- The Human Metabolome Database
- HMDBP01612
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Cell membrane
- Disease variant
- Endoplasmic reticulum
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Sodium transport
- Symport
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| brush border membrane |
| extracellular exosome |
| endoplasmic reticulum |
| cytosol |
| basal plasma membrane |
| apical plasma membrane |
| cytoplasm |
| plasma membrane |
Sequence
MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSSAWRNHTVPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQMLRVKGMKHRKTPSHTRMLKDGQERPTILKSTAF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 57 | N-linked (GlcNAc...) asparagine | |||
| 64 | N-linked (GlcNAc...) asparagine | |||
| 91 | N-linked (GlcNAc...) asparagine |
G27058EU
G70441OD
G83460ZZ
G80920RR
G62765YT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Carnitine shuttle | Homo sapiens |
| Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP) | Homo sapiens |
| Organic cation transport | Homo sapiens |
