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Acetylcholine receptor subunit alpha-type des-2

Summary

UniProt ID: O76554
Gene Symbol: des-2 T26H10.1 acr-4
Gene ID: 179574
Organism: Caenorhabditis elegans

External Links

Re-Glyco: O76554

Annotation

Keyword: Cell membrane Glycoprotein Ligand-gated ion channel Receptor Reference proteome Signal Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	Reference
chemical synaptic transmission
ion transmembrane transport	IBA	GO_REF
monoatomic ion transmembrane transport	IBA	GO_REF
ion transmembrane transport	IEA	GO_REF
monoatomic ion transmembrane transport	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

transmembrane transport [inference]

monoatomic ion transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of biological quality [inference]

regulation of membrane potential

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	Reference
plasma membrane	IDA	PMID
plasma membrane	IBA	GO_REF
plasma membrane	IEA	GO_REF
neuron projection	IBA	GO_REF
synapse	IBA	GO_REF

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex

transporter complex [inference]

transmembrane transporter complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

postsynapse

Displaying **all 3** entries
GO Term	Evidence Code	Reference
transmembrane signaling receptor activity	IEA	GO_REF
excitatory extracellular ligand-gated monoatomic ion channel activity
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

neurotransmitter receptor activity [inference]

transmitter-gated channel activity [inference]

transmitter-gated monoatomic ion channel activity [inference]

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MLIIIQSLLLATTASLCIADTPVPTQIRLVHDLLDNYDKKAKPMWDNSKPINVSFSMDLYQILELNEPQQYILLNAWIIERWFDEFLYWNPDDYENITELRLPYDSIWLPDTTLYNSLVMKDDDTRRLLNSKLTTDTHRRAALIELLYPTIYKFSCLLDLRFFPFDVQVCTMTFSSWTYDQKGIDYFPYSDKIGTSNYLENEGWYILQTKIKRQEVKYACCPNNYTLLQLTLYLRRKPLFYLVNLIIPTSIITLIAIVGFFTTSSASGMREEKVSLGITTLLSMSILMLMVSDQMPTTSTFIPLIGWFILAMIIVISLGTVVSSVIIAIQKRGSLGERMSKRALKFAKVLAWFTCTSLPPHVEKEHMMEAFDAPTPLVEVRPLQLASVKESVRNKWVSGARRATQRGNSGLALISDKSTDPLIHLSPTAHQPDESISPSAPPVPSSSPLPPPLTPGPADDVVSVASELSSKFLTSRMRPKSQKDNTFAAMQSSIKANRQLAVAEFEWFATVVERTCFVIFVVAFLIITFGINFIGFIHWHQAGVEYGG

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	Source
52	N-linked (GlcNAc...) asparagine	UniProt
96	N-linked (GlcNAc...) asparagine	UniProt
224	N-linked (GlcNAc...) asparagine	UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 2** entries
Pathway Name	Organism
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Caenorhabditis elegans
Neurotransmitter receptors and postsynaptic signal transmission	Caenorhabditis elegans

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