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Sortilin-related receptor

Summary

UniProt ID

O88307

Gene Symbol

Sorl1

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003201

GlyConnect

2735

GlyGen

O88307

O-GlcNAcAtlas

O88307

Annotation

Keyword

Cell membrane
Cleavage on pair of basic residues
Cytoplasmic vesicle
Developmental protein
Disulfide bond
EGF-like domain
Endocytosis
Endoplasmic reticulum
Endosome
Glycoprotein
Golgi apparatus
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix
Transport

Gene Ontology (GO)

Displaying entries **11 - 20** of 30 in total

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GO Term
positive regulation of glial cell-derived neurotrophic factor production
negative regulation of amyloid-beta formation
positive regulation of ER to Golgi vesicle-mediated transport
positive regulation of early endosome to recycling endosome transport
negative regulation of amyloid precursor protein catabolic process
negative regulation of neurofibrillary tangle assembly
adaptive thermogenesis
protein targeting
protein targeting to lysosome
receptor-mediated endocytosis

Displaying entries **1 - 10** of 22 in total

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GO Term
Golgi membrane
endosome
early endosome
endoplasmic reticulum
endoplasmic reticulum membrane
Golgi apparatus
trans-Golgi network
cell surface
Golgi cisterna
perinuclear region of cytoplasm

Displaying **all 6** entries
GO Term
transmembrane signaling receptor activity
amyloid-beta binding
aspartic-type endopeptidase inhibitor activity
low-density lipoprotein particle binding
neuropeptide binding
small GTPase binding

Annotation information from UniProt.

Sequence

MATRSSRRESRLPFLFALVALLPRGALGGGWTQRLHGGPAPLPQDRGFFVVQGDPRDLRLGTHGDAPGASPAARKPLRTRRSAALQPQPIQVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYDYGKSFSKISEKLNFGVGNNSEAVISQFYHSPADNKRYIFVDAYAQYLWITFDFCSTIHGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKSFSWGIDPYDQPNAIYIERHEPFGFSTVLRSTDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLPGSQQQSSVQLWVSFGRKPMRAAQFVTKHPINEYYIADAAEDQVFVCVSHSNNSTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQGMETNELKYSTNEGETWKTFVFSEKPVFVYGLLTEPGEKSTVFTIFGSNKESVHSWLILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIYRYDLASGATEQLPLSGLRAAVALDFDYERNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFEPLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSYMDGSAAYRLVSEDVKWPNGISVDSQWIYWTDAYLDCIERITFSGQQRSVILDSLPHPYAIAVFKNEIYWDDWSQLSIFRASKHSRSQVEILASQLTGLMDMKVFYKGKNAGSNACVPQPCSLLCLPKANNSKSCRCPEGVASSVLPSGDLMCDCPQGYQRKNNTCVKEENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTVCDADTQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPVSCEKKCNGFHCPNGTCIPSSKHCDGLRDCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIVQCRDGSDEDAAFAGCSQDPEFHKECDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGHCIPNRWKCDRENDCGDWSDEKDCGDSHVLPSPTPGPSTCLPNYFHCSSGACVMGTWVCDGYRDCADGSDEEACPSLANSTAASTPTQFGQCDRFEFECHQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCTSREFKCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTSTVLKVLKPDTTYQVKVQVHCLNKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWAPPVHTHGLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQAPNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLSFRGGSALSHRVSNLTAHTSYEISAWAKTDLGDSPLAFEHILTRGSSPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSVTTSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVHIGKTSALIKWESPYDSPDQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVLLFWKSLALKEKQFNETRGYEIHMSDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQARCLFGSQICGEPAVLLYDELSSGADAAVIQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSFSAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 31 in total

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Position	Description	GlyTouCan ID	Source
99	N-linked (GlcNAc...) asparagine		UniProt GlyGen
158	N-linked (GlcNAc...) asparagine	G29184RN G48584BU G70101JE G64527OM G82119TF G06110VR	GlycoProtDB UniProt GlyGen GlyConnect
367	N-linked (GlcNAc...) asparagine	G22328UA	UniProt GlyGen
368	N-linked (GlcNAc...) asparagine		UniProt GlyGen
430	N-linked (GlcNAc...) asparagine	G02886BB	UniProt GlyGen
616	N-linked (GlcNAc...) asparagine		UniProt GlyGen
674	N-linked (GlcNAc...) asparagine	G48584BU G80920RR G74430RZ G06110VR	UniProt GlyGen GlyConnect
818	N-linked (GlcNAc...) asparagine		UniProt GlyGen
871	N-linked (GlcNAc...) asparagine	G80920RR G06110VR G66538GV	GlycoProtDB UniProt GlyGen GlyConnect
1035	N-linked (GlcNAc...) asparagine		UniProt GlyGen