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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Inhibitor of nuclear factor kappa-B kinase subunit beta
Summary
- UniProt ID
- O88351
- Gene Symbol
-
- Ikbkb
- Ikkb
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Cytoplasm
- Hydroxylation
- Isopeptide bond
- Membrane
- Nucleus
- Phosphoprotein
- Reference proteome
- S-nitrosylation
- Serine/threonine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| cytoplasmic side of plasma membrane |
| membrane raft |
| IkappaB kinase complex |
| CD40 receptor complex |
Sequence
MSWSPSLPTQTCGAWEMKERLGTGGFGNVIRWHNQATGEQIAIKQCRQELSPKNRNRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRRYLNQFENCCGLREGAVLTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGAVKFSSSLPFPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPQYGPNGCFRALDDILNLKLVHVLNMVTGTVHTYPVTEDESLQSLKTRIQENTGILETDQELLQKAGLVLLPDKPATQCISDSKTNEGLTLDMDLVFLLDNSKINYETQITPRPPPESVSCILQEPKRNLSFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMSLLRNNSCLSKMKNAMASTAQQLKAKLDFFKTSIQIDLEKYKEQTEFGITSDKLLLAWREMEQAVEQCGRENDVKHLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRKLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDERTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNVSRLSHPGQLMSQPSSACDSLPESDKKSEELVAEAHALCSRLESALQDTVKEQDRSFTTLDWSWLQMEDEERCSLEQACD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 600 |
|
|||
| 733 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PKR-mediated signaling | Mus musculus |
| RIP-mediated NFkB activation via ZBP1 | Mus musculus |
| Regulation of NF-kappa B signaling | Mus musculus |
| Regulation of TNFR1 signaling | Mus musculus |
| SLC15A4:TASL-dependent IRF5 activation | Mus musculus |
| TAK1-dependent IKK and NF-kappa-B activation | Mus musculus |
| TNFR1-induced NF-kappa-B signaling pathway | Mus musculus |
| TRAF6 mediated NF-kB activation | Mus musculus |
| Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells | Mus musculus |
| p75NTR recruits signalling complexes | Mus musculus |
