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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Catechol O-methyltransferase
Summary
- UniProt ID
- O88587
- Gene Symbol
-
- Comt
- Comt1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Alternative initiation
- Catecholamine metabolism
- Cell membrane
- Cytoplasm
- Lipid metabolism
- Magnesium
- Metal-binding
- Methyltransferase
- Neurotransmitter degradation
- Phosphoprotein
- Reference proteome
- S-adenosyl-L-methionine
- Signal-anchor
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| mastication |
| response to salt |
| response to dopamine |
| response to corticosterone |
| cellular response to phosphate starvation |
| response to food |
| habituation |
| response to pain |
| response to hypoxia |
| startle response |
| GO Term |
|---|
| membrane |
| axon |
| postsynaptic membrane |
| dendrite |
| vesicle |
| cell body |
| postsynapse |
| glutamatergic synapse |
| mitochondrion |
| cytosol |
| GO Term |
|---|
| catechol O-methyltransferase activity |
| magnesium ion binding |
| L-dopa O-methyltransferase activity |
| orcinol O-methyltransferase activity |
Sequence
MLLAAVSLGLLLLAFLLLLRHLGWGLVAIGWFEFVQQPVHNLLMGGTKEQRILRHVQQHAKPGDPQSVLEAIDTYCSEKEWAMNVGDAKGQIMDAVIREYRPSLVLELGAYCGYSAVRMARLLPPGARLLTMEINPDYAAITQQMLDFAGLQDKVSILIGASQDLIPQLKKKYDVDTLDMVFLDHWKDRYLPDTLLLEECGLLRKGTVLLADNVIVPGTPDFLAYVRGSSSFECTHYSSYLEYMKVVDGLEKAVYQGPGSSPVKS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Enzymatic degradation of Dopamine by monoamine oxidase | Mus musculus |
| Enzymatic degradation of dopamine by COMT | Mus musculus |
| Methylation | Mus musculus |
