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Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

Summary

UniProt ID

O88703

Gene Symbol

Hcn2
Bcng2
Hac1

Organism

Mus musculus (house mouse)

External Links

GlyGen: O88703
PubChem: O88703
The O-GlcNAc Database: O88703
O-GlcNAcAtlas: O88703

Annotation

Keyword

3D-structure
Ammonia transport
Cell membrane
Glycoprotein
Ligand-gated ion channel
Methylation
Palmitate
Phosphoprotein
Potassium channel
Reference proteome
Sodium channel
Transmembrane helix
Voltage-gated channel
cAMP-binding

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
regulation of membrane depolarization
regulation of membrane potential
sodium ion transmembrane transport
sodium ion import across plasma membrane
potassium ion transmembrane transport
potassium ion import across plasma membrane
cellular response to cAMP
cellular response to cGMP

Displaying **all 9** entries
GO Term
plasma membrane
membrane
axon
dendrite
dendrite membrane
somatodendritic compartment
neuronal cell body
dendritic shaft
HCN channel complex

Displaying **all 8** entries
GO Term
protein-containing complex binding
molecular adaptor activity
PDZ domain binding
identical protein binding
cAMP binding
intracellular cAMP-activated cation channel activity
voltage-gated sodium channel activity
voltage-gated potassium channel activity

Annotation information from UniProt.

Sequence

MDARGGGGRPGDSPGTTPAPGPPPPPPPPAPPQPQPPPAPPPNPTTPSHPESADEPGPRARLCSRDSACTPGAAKGGANGECGRGEPQCSPEGPARGPKVSFSCRGAASGPSAAEEAGSEEAGPAGEPRGSQASFLQRQFGALLQPGVNKFSLRMFGSQKAVEREQERVKSAGAWIIHPYSDFRFYWDFTMLLFMVGNLIIIPVGITFFKDETTAPWIVFNVVSDTFFLMDLVLNFRTGIVIEDNTEIILDPEKIKKKYLRTWFVVDFVSSIPVDYIFLIVEKGIDSEVYKTARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMTYDLASAVMRICNLISMMLLLCHWDGCLQFLVPMLQDFPSDCWVSINNMVNHSWSELYSFALFKAMSHMLCIGYGRQAPESMTDIWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSILGELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDRIGKKNSILLHKVQHDLSSGVFNNQENAIIQEIVKYDREMVQQAELGQRVGLFPPPPPPQVTSAIATLQQAVAMSFCPQVARPLVGPLALGSPRLVRRAPPGPLPPAASPGPPAASPPAAPSSPRAPRTSPYGVPGSPATRVGPALPARRLSRASRPLSASQPSLPHGVPAPSPAASARPASSSTPRLGPAPTARTAAPSPDRRDSASPGAASGLDPLDSARSRLSSNL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites