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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
Summary
- UniProt ID
- O88962
- Gene Symbol
-
- Cyp8b1
- Cyp12
- Organism
- Mus musculus (house mouse)
External Links
- GlyGen
- O88962
- PubChem
- O88962
- The Human Metabolome Database
- HMDBP12357
- The O-GlcNAc Database
- O88962
Annotation
- Keyword
-
- Heme
- Microsome
- Monooxygenase
- Phosphoprotein
- Reference proteome
- Steroid biosynthesis
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| bile acid biosynthetic process |
| positive regulation of intestinal cholesterol absorption |
| GO Term |
|---|
| endoplasmic reticulum membrane |
Sequence
MTLWCTVLGALLTVVGCLCLSLLLRHRRPWEPPLDKGFVPWLGHSMAFRKNMFEFLKGMRAKHGDVFTVQLGGQYFTFVMDPLSFGPIIKNTEKALDFQSYAKELVLKVFGYQSVDGDHRMIHLASTKHLMGQGLEELNQAMLDSLSLVMLGPKGSSLGASSWCEDGLFHFCYRILFKAGFLSLFGYTKDKQQDLDEADELFRKFRRFDFLFPRFVYSLLGPREWVEVSQLQRLFHQRLSVEQNLEKDGISCWLGYMLQFLREQGIASSMQDKFNFMMLWASQGNTGPTCFWVLLFLLKHQDAMKAVREEATRVMGKARLEAKKSFTFTPSALKHTPVLDSVMEESLRLCATPTLLRVVQEDYVLKMASGQEYQIRRGDKVALFPYLSVHMDPDIHPEPTAFKYDRFLNPDGTRKVDFYKSGKKIHHYSMPWGSGVSKCPGRFFALSEMKTFVLLMIMYFDFKLVDPDIPVPPIDPRRWGFGTSQPSHEVRFLYRLKPVQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Eicosanoids | Mus musculus |
| Nicotinamide salvaging | Mus musculus |
| Sterols are 12-hydroxylated by CYP8B1 | Mus musculus |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) | Mus musculus |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | Mus musculus |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | Mus musculus |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol | Mus musculus |
