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ATP-dependent DNA helicase Q5

Summary

UniProt ID

O94762

Gene Symbol

RECQL5
RECQ5

Organism

Homo sapiens (human)

External Links

GlyGen: O94762
PubChem: O94762
The Human Metabolome Database: HMDBP11908
The O-GlcNAc Database: O94762
O-GlcNAcAtlas: O94762

Annotation

Keyword

3D-structure
Alternative splicing
Cell division
Cytoplasm
DNA repair
DNA replication
DNA-binding
Helicase
Isomerase
Metal-binding
Nucleus
Phosphoprotein
Reference proteome
Zinc

Gene Ontology (GO)

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GO Term
mitotic cell cycle
DNA metabolic process
DNA unwinding involved in DNA replication
cellular response to xenobiotic stimulus
negative regulation of transcription elongation by RNA polymerase II
chromosome separation
cellular response to camptothecin
negative regulation of double-strand break repair via homologous recombination
cell division
replication-born double-strand break repair via sister chromatid exchange

Displaying **all 7** entries
GO Term
nucleus
chromosome
cytoplasm
cytosol
nucleoplasm
replication fork
transcription preinitiation complex

Displaying entries **1 - 10** of 11 in total

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GO Term
DNA binding
ATP binding
four-way junction helicase activity
metal ion binding
identical protein binding
3'-5' DNA helicase activity
isomerase activity
ATP hydrolysis activity
RNA polymerase II complex binding
DNA helicase activity

Annotation information from UniProt.

Sequence

MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELGCRHAAIAKYFGDALPACAKGCDHCQNPTAVRRRLEALERSSSWSKTCIGPSQGNGFDPELYEGGRKGYGDFSRYDEGSGGSGDEGRDEAHKREWNLFYQKQMQLRKGKDPKIEEFVPPDENCPLKEASSRRIPRLTVKAREHCLRLLEEALSSNRQSTRTADEADLRAKAVELEHETFRNAKVANLYKASVLKKVADIHRASKDGQPYDMGGSAKSCSAQAEPPEPNEYDIPPASHVYSLKPKRVGAGFPKGSCPFQTATELMETTRIREQAPQPERGGEHEPPSRPCGLLDEDGSEPLPGPRGEVPGGSAHYGGPSPEKKAKSSSGGSSLAKGRASKKQQLLATAAHKDSQSIARFFCRRVESPALLASAPEAEGACPSCEGVQGPPMAPEKYTGEEDGAGGHSPAPPQTEECLRERPSTCPPRDQGTPEVQPTPAKDTWKGKRPRSQQENPESQPQKRPRPSAKPSVVAEVKGSVSASEQGTLNPTAQDPFQLSAPGVSLKEAANVVVKCLTPFYKEGKFASKELFKGFARHLSHLLTQKTSPGRSVKEEAQNLIRHFFHGRARCESEADWHGLCGPQR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites