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MIRAGE
EGF-containing fibulin-like extracellular matrix protein 2

Summary
UniProt ID
O95967
Gene Symbol
  • EFEMP2
  • FBLN4
  • UNQ200/PRO226
Gene ID
30008
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011268
GlyConnect
GlyGen
O95967
PubChem
O95967
The Human Metabolome Database
HMDBP13403
Re-Glyco
O95967
Annotation
Keyword
  • 3D-structure
  • Basement membrane
  • Calcium
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • EGF-like domain
  • Glycoprotein
  • Reference proteome
  • Repeat
  • Signal
Gene Ontology (GO)
Displaying all 8 entries
GO Term
extracellular exosome
microfibril
elastic fiber
extracellular vesicle
extracellular region
basement membrane
extracellular matrix
collagen-containing extracellular matrix
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MLPCASCLPGSLLLWALLLLLLGSASPQDSEEPDSYTECTDGYEWDPDSQHCRDVNECLTIPEACKGEMKCINHYGGYLCLPRSAAVINDLHGEGPPPPVPPAQHPNPCPPGYEPDDQDSCVDVDECAQALHDCRPSQDCHNLPGSYQCTCPDGYRKIGPECVDIDECRYRYCQHRCVNLPGSFRCQCEPGFQLGPNNRSCVDVNECDMGAPCEQRCFNSYGTFLCRCHQGYELHRDGFSCSDIDECSYSSYLCQYRCINEPGRFSCHCPQGYQLLATRLCQDIDECESGAHQCSEAQTCVNFHGGYRCVDTNRCVEPYIQVSENRCLCPASNPLCREQPSSIVHRYMTITSERSVPADVFQIQATSVYPGAYNAFQIRAGNSQGDFYIRQINNVSAMLVLARPVTGPREYVLDLEMVTMNSLMSYRASSVLRLTVFVGAYTF
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
198 N-linked (GlcNAc...) asparagine
394 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Molecules associated with elastic fibres Homo sapiens
Disease
Displaying all 5 entries
DO ID Disease Name Source
DOID:0050645 arterial tortuosity syndrome
DOID:0070133 autosomal recessive cutis laxa type IB
DOID:1380 endometrial cancer
DOID:3347 osteosarcoma
DOID:3627 aortic aneurysm
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025