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B-cell lymphoma/leukemia 10

Summary

UniProt ID

O95999

Gene Symbol

BCL10
CIPER
CLAP

Organism

Homo sapiens (human)

External Links

GlyGen: O95999
PubChem: O95999
The O-GlcNAc Database: O95999

Annotation

Keyword

3D-structure
Acetylation
Adaptive immunity
Apoptosis
Chromosomal rearrangement
Cytoplasm
Disease variant
Innate immunity
Isopeptide bond
Membrane
Phosphoprotein
Reference proteome
Tumor suppressor
Ubl conjugation

Gene Ontology (GO)

Displaying entries **21 - 30** of 33 in total

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GO Term
positive regulation of DNA-templated transcription
positive regulation of NF-kappaB transcription factor activity
toll-like receptor signaling pathway
lipopolysaccharide-mediated signaling pathway
non-canonical NF-kappaB signal transduction
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of lymphotoxin A production
protein homooligomerization
cellular response to mechanical stimulus
positive regulation of extrinsic apoptotic signaling pathway

Displaying entries **1 - 10** of 11 in total

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GO Term
nucleus
cytoplasm
lysosome
cytoplasmic microtubule
membrane raft
immunological synapse
polkadots
CBM complex
perinuclear region of cytoplasm
protein-containing complex

Displaying entries **1 - 10** of 11 in total

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GO Term
protein-containing complex binding
kinase activator activity
NF-kappaB binding
CARD domain binding
ubiquitin protein ligase binding
identical protein binding
protein kinase B binding
protease binding
transcription coactivator activity
general transcription initiation factor binding

Annotation information from UniProt.

Sequence

MEPTAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFPDGATNNLSRSNSDESNFSEKLRASTVMYHPEGESSTTPFFSTNSSLNLPVLEVGRTENTIFSSTTLPRPGDPGAPPLPPDLQLEEEGTCANSSEMFLPLRSRTVSRQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 5** entries
Pathway Name	Organism
Activation of NF-kappaB in B cells	Homo sapiens
CLEC7A (Dectin-1) signaling	Homo sapiens
Downstream TCR signaling	Homo sapiens
E3 ubiquitin ligases ubiquitinate target proteins	Homo sapiens
FCERI mediated NF-kB activation	Homo sapiens