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G1/S-specific cyclin-E2

Summary

UniProt ID

O96020

Gene Symbol

CCNE2

Gene ID

9134

Organism

Homo sapiens (human)

External Links

GlyGen: O96020
PubChem: O96020
The O-GlcNAc Database: O96020
O-GlcNAcAtlas: O96020
Re-Glyco: O96020

Annotation

Keyword

3D-structure
Alternative splicing
Cell division
Cyclin
Nucleus
Phosphoprotein
Reference proteome

Gene Ontology (GO)

Displaying **all 7** entries
GO Term
microtubule organizing center
nucleus
cytoplasm
nucleoplasm
cytosol
cyclin E1-CDK2 complex
cyclin E2-CDK2 complex

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 8** entries
GO Term
G1/S transition of mitotic cell cycle
DNA replication initiation
homologous chromosome pairing at meiosis
regulation of protein localization
cell division
positive regulation of G1/S transition of mitotic cell cycle
regulation of cyclin-dependent protein serine/threonine kinase activity
telomere maintenance

Displaying **all 2** entries
GO Term
cyclin-dependent protein serine/threonine kinase regulator activity
protein kinase binding

Annotation information from UniProt.

Sequence

MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPPVLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTHTNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
35			G49108TO	GlyGen The O-GlcNAc Database
36			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 11 in total

1

2

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Pathway Name	Organism
Association of TriC/CCT with target proteins during biosynthesis	Homo sapiens
CDK-mediated phosphorylation and removal of Cdc6	Homo sapiens
Cyclin D associated events in G1	Homo sapiens
Cyclin E associated events during G1/S transition	Homo sapiens
DNA Damage/Telomere Stress Induced Senescence	Homo sapiens
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Homo sapiens
G0 and Early G1	Homo sapiens
Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	Homo sapiens
SCF(Skp2)-mediated degradation of p27/p21	Homo sapiens
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	Homo sapiens