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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Cytochrome P450 1A2
Summary
- UniProt ID
- P00186
- Gene Symbol
-
- Cyp1a2
- Cyp1a-2
- Organism
- Mus musculus (house mouse)
External Links
- PubChem
- P00186
Annotation
- Keyword
-
- Direct protein sequencing
- Fatty acid metabolism
- Glycoprotein
- Heme
- Lyase
- Membrane
- Microsome
- Monooxygenase
- Reference proteome
- Sterol metabolism
- Gene Ontology (GO)
| GO Term |
|---|
| intracellular membrane-bounded organelle |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| caffeine oxidase activity |
| estrogen 16-alpha-hydroxylase activity |
| estrogen 2-hydroxylase activity |
| hydroperoxy icosatetraenoate dehydratase activity |
Sequence
MAFSQYISLAPELLLATAIFCLVFWMVRASRTQVPKGLKNPPGPWGLPFIGHMLTVGKNPHLSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSASSCYLEEHVSKEANHLVSKLQKAMAEVGHFEPVSQVVESVANVIGAMCFGKNFPRKSEEMLNIVNNSKDFVENVTSGNAVDFFPVLRYLPNPALKRFKTFNDNFVLFLQKTVQEHYQDFNKNSIQDITSALFKHSENYKDNGGLIPEEKIVNIVNDIFGAGFDTVTTAITWSILLLVTWPNVQRKIHEELDTVVGRDRQPRLSDRPQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKERCIYINQWQVNHDEKQWKDPFVFRPERFLTNNNSAIDKTQSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLQHLEFSVPPGVKVDLTPNYGLTMKPGTCEHVQAWPRFSK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 68 | O-linked (GlcNAc) serine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Aflatoxin activation and detoxification | Mus musculus |
| Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 | Mus musculus |
| Biosynthesis of maresin-like SPMs | Mus musculus |
| Biosynthesis of protectins | Mus musculus |
| Methylation | Mus musculus |
| Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) | Mus musculus |
| Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) | Mus musculus |
