L-lactate dehydrogenase A chain

Summary
UniProt ID
P00338
Gene Symbol
  • LDHA
Organism
Homo sapiens (human)
External Links
GlyGen
P00338
PubChem
P00338
The Human Metabolome Database
HMDBP03579
The O-GlcNAc Database
P00338
RaftProt
P00338
O-GlcNAcAtlas
P00338
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Direct protein sequencing
  • Disease variant
  • Glycogen storage disease
  • Isopeptide bond
  • NAD
  • Oxidoreductase
  • Phosphoprotein
  • Reference proteome
  • Ubl conjugation
Gene Ontology (GO)
Sequence
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
Glycosylation Sites
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Pyruvate metabolism Homo sapiens
Regulation of pyruvate metabolism Homo sapiens
Disease
Displaying entries 1 - 10 of 243 in total
DO ID Disease Name Source
DOID:0070328 adult hepatocellular carcinoma
DOID:0050156 idiopathic pulmonary fibrosis
DOID:0050387 nonpapillary renal cell carcinoma
DOID:0050646 distal arthrogryposis
DOID:0050700 cardiomyopathy
DOID:0050902 medulloblastoma
DOID:0060058 lymphoma
DOID:0060161 Kennedy's disease
DOID:0070322 childhood hepatocellular carcinoma
DOID:0080108 myoglobinuria

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024