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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Prothrombin
Summary
- UniProt ID
- P00735
- Gene Symbol
-
- F2
- Organism
- Bos taurus (domestic cattle)
External Links
- GlyConnect
- PubChem
- P00735
- The Human Metabolome Database
- HMDBP13489
Annotation
- Keyword
-
- 3D-structure
- Acute phase
- Blood coagulation
- Calcium
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disulfide bond
- Gamma-carboxyglutamic acid
- Glycoprotein
- Kringle
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| platelet activation |
| positive regulation of blood coagulation |
| acute-phase response |
| protein polymerization |
| GO Term |
|---|
| extracellular space |
| collagen-containing extracellular matrix |
| GO Term |
|---|
| serine-type endopeptidase activity |
| calcium ion binding |
| fibrinogen binding |
Sequence
MARVRGPRLPGCLALAALFSLVHSQHVFLAHQQASSLLQRARRANKGFLEEVRKGNLERECLEEPCSREEAFEALESLSATDAFWAKYTACESARNPREKLNECLEGNCAEGVGMNYRGNVSVTRSGIECQLWRSRYPHKPEINSTTHPGADLRENFCRNPDGSITGPWCYTTSPTLRREECSVPVCGQDRVTVEVIPRSGGSTTSQSPLLETCVPDRGREYRGRLAVTTSGSRCLAWSSEQAKALSKDQDFNPAVPLAENFCRNPDGDEEGAWCYVADQPGDFEYCDLNYCEEPVDGDLGDRLGEDPDPDAAIEGRTSEDHFQPFFNEKTFGAGEADCGLRPLFEKKQVQDQTEKELFESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDRLGS
Glycosylation Sites
G57173NZ
G87457SB
G28916LJ
G29130SY
G48414YA
G84467IZ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
