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Complement factor B

Summary

UniProt ID

P00751

Gene Symbol

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011283

GlyConnect

GlyGen

P00751

PubChem

P00751

The O-GlcNAc Database

P00751

RaftProt

P00751

Annotation

Keyword

3D-structure
Age-related macular degeneration
Alternative splicing
Cleavage on pair of basic residues
Complement alternate pathway
Direct protein sequencing
Disease variant
Disulfide bond
Glycation
Hemolytic uremic syndrome
Reference proteome
Repeat
Secreted
Serine protease
Signal
Sushi
Zymogen

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
complement activation
complement activation, alternative pathway
response to bacterium
proteolysis

Displaying **all 6** entries
GO Term
classical-complement-pathway C3/C5 convertase complex
blood microparticle
extracellular region
extracellular space
plasma membrane
extracellular exosome

Displaying **all 2** entries
GO Term
complement binding
serine-type endopeptidase activity

Annotation information from UniProt.

Sequence

MGSNLSPQLCLMPFILGLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGASNFTGAKKCLVNLIEKVASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNEINYEDHKLKSGTNTKKALQAVYSMMSWPDDVPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPREDYLDVYVFGVGPLVNQVNINALASKKDNEQHVFKVKDMENLEDVFYQMIDESQSLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDEDLGFL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
25			G53434XO	GlyGen
26			G43417UB G57321FI	GlyGen
122	N-linked (GlcNAc...) asparagine	16335952 17310251 19159218 6546754	G63980BQ G04854VP G94470IW G85554PZ G14972EH G43223CG G58954YZ G26330YA G08918WF G00912UN G48414YA G87389XI G92551JA G61256FT G15664MX G70619PT G06356OH G59626AS G80920RR G01485JJ G82463GQ G10486CT G72291OX G95865ZB G06110VR G57317CE G28681TP G15407YE G32550BI G54010QB G98129XB	GlycoProtDB UniProt GlyGen GlyConnect
142	N-linked (GlcNAc...) asparagine	17310251 19574954 6546754	G96416FQ	UniProt GlyGen GlyConnect
285	N-linked (GlcNAc...) asparagine	16335952 17310251 19159218 6546754	G94665LC G11115RO G70232NH G06247RL G75418YA G28622IK G40206WX G63980BQ G04854VP G94470IW G92135MA G98611JV G40834TG G43669FQ G45395BF G59324HL G85554PZ G10819WX G40926MX G14972EH G43223CG G58954YZ G37412TK G54612UD G31986NC G26330YA G10846ZT G40574BA G82830MN G00273SJ G05933EN G08918WF G47737VJ G00912UN G48414YA G61256FT G84452RH G60033FS G41071NU G86182NS G49018RC G72747WU G70619PT G06356OH G59626AS G10486CT G54010QB	GlycoProtDB UniProt GlyGen GlyConnect
291	N-linked (Glc) (glycation) lysine	2006911		UniProt
378	N-linked (GlcNAc...) asparagine	16335952 17310251 19574954 6546754	G12341GU G70232NH G70888PK G06247RL G04854VP G94470IW G40834TG G45395BF G88374WZ G10819WX G40926MX G56307ZW G14972EH G43223CG G58954YZ G37412TK G31986NC G26330YA G10846ZT G40574BA G82830MN G78787DI G00273SJ G08918WF G47737VJ G00912UN G48414YA G58087IP G87389XI G15664MX G46691LC G27126ED G27058EU G29184RN G96091TT G60033FS G41071NU G49018RC G46902YN G72747WU G70619PT G06356OH G59626AS G08290VR G01650EU G10486CT G95865ZB G57776ZU G84349RE G54010QB G84225JN	GlycoProtDB UniProt GlyGen GlyConnect
			G49108TO	GlyGen The O-GlcNAc Database