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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Protransforming growth factor alpha
Summary
- UniProt ID
- P01135
- Gene Symbol
-
- TGFA
- Organism
- Homo sapiens (human)
External Links
- PubChem
- P01135
- The Human Metabolome Database
- HMDBP12416
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Growth factor
- Mitogen
- Palmitate
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| hepatocyte proliferation |
| epidermal growth factor receptor signaling pathway |
| positive regulation of peptidyl-tyrosine phosphorylation |
Sequence
MVPSAGQLALFALGIVLAACQALENSTSPLSADPPVAAAVVSHFNDCPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLAVVAASQKKQAITALVVVSIVALAVLIITCVLIHCCQVRKHCEWCRALICRHEKPSALLKGRTACCHSETVV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 25 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| GAB1 signalosome | Homo sapiens |
| GRB2 events in EGFR signaling | Homo sapiens |
| Inhibition of Signaling by Overexpressed EGFR | Homo sapiens |
| PI3K/AKT Signaling | Homo sapiens |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| SHC1 events in EGFR signaling | Homo sapiens |
| Signaling by EGFR | Homo sapiens |
| TFAP2 (AP-2) family regulates transcription of growth factors and their receptors | Homo sapiens |
