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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Transforming growth factor beta-1 proprotein
Summary
- UniProt ID
- P01137
- Gene Symbol
-
- TGFB1
- TGFB
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011299
- GlyConnect
- GlyGen
- P01137
- PubChem
- P01137
- The Human Metabolome Database
- HMDBP14566
- RaftProt
- P01137
Annotation
- Keyword
-
- 3D-structure
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Growth factor
- Mitogen
- Reference proteome
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| negative regulation of cell growth |
| osteoclast differentiation |
| regulation of cell migration |
| positive regulation of cell migration |
| GO Term |
|---|
| plasma membrane |
| axon |
| extracellular matrix |
Sequence
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 82 | N-linked (GlcNAc...) asparagine | |||
| 136 | N-linked (GlcNAc...) asparagine | |||
| 176 | N-linked (GlcNAc...) asparagine |
G27058EU
G25079LO
G80920RR
G01485JJ
G14260UH
G62765YT
G31852PQ
G28622IK
G41247ZX
G02815KT
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cell surface interactions at the vascular wall | Homo sapiens |
| Downregulation of TGF-beta receptor signaling | Homo sapiens |
| ECM proteoglycans | Homo sapiens |
| Influenza Virus Induced Apoptosis | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Molecules associated with elastic fibres | Homo sapiens |
| Platelet degranulation | Homo sapiens |
| RUNX3 regulates CDKN1A transcription | Homo sapiens |
| RUNX3 regulates p14-ARF | Homo sapiens |
| Regulation of RUNX3 expression and activity | Homo sapiens |
