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Pro-opiomelanocortin

Summary

UniProt ID

P01193

Gene Symbol

Pomc
Pomc1

Gene ID

18976

Organism

Mus musculus (house mouse)

External Links

GlyConnect

Pro-opiomelanocortin

GlyGen

P01193

PubChem

P01193

Re-Glyco

P01193

Annotation

Keyword

Acetylation
Amidation
Cleavage on pair of basic residues
Endorphin
Glycoprotein
Hormone
Phosphoprotein
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
cytoplasm
secretory granule
extracellular region
extracellular space

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 16 in total

1

2

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GO Term
negative regulation of tumor necrosis factor production
neuropeptide signaling pathway
calcium-mediated signaling
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
generation of precursor metabolites and energy
signal transduction
cell-cell signaling
regulation of blood pressure
regulation of appetite
glucose homeostasis

Displaying **all 5** entries
GO Term
hormone activity
G protein-coupled receptor binding
type 3 melanocortin receptor binding
type 4 melanocortin receptor binding
type 1 melanocortin receptor binding

Annotation information from UniProt.

Sequence

MPRFCYSRSGALLLALLLQTSIDVWSWCLESSQCQDLTTESNLLACIRACKLDLSLETPVFPGNGDEQPLTENPRKYVMGHFRWDRFGPRNSSSAGSAAQRRAEEEAVWGDGSPEPSPREGKRSYSMEHFRWGKPVGKKRRPVKVYPNVAENESAEAFPLEFKRELEGERPLGLEQVLESDAEKDDGPYRVEHFRWSNPPKDKRYGGFMTSEKSQTPLVTLFKNAIIKNAHKKGQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	Description	GlyTouCan ID	Source
91	N-linked (GlcNAc...) asparagine	G41071NU	UniProt GlyGen
152	N-linked (GlcNAc...) asparagine	G93910IH G14260UH G64527OM	UniProt GlyGen GlyConnect
		G46422KL G50487BS G49743VF G57196QI G32673DL G45700OA	GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Androgen biosynthesis	Mus musculus
Endogenous sterols	Mus musculus
G alpha (i) signalling events	Mus musculus
G alpha (s) signalling events	Mus musculus
G-protein activation	Mus musculus
Glucocorticoid biosynthesis	Mus musculus
Opioid Signalling	Mus musculus
Peptide hormone biosynthesis	Mus musculus
Peptide ligand-binding receptors	Mus musculus