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Interferon beta

Summary

UniProt ID

P01574

Gene Symbol

IFB
IFNB
IFNB1

Gene ID

3456

Organism

Homo sapiens (human)

External Links

GlyConnect

Interferon beta

GlyGen

P01574

PubChem

P01574

The Human Metabolome Database

HMDBP02832

Re-Glyco

P01574

Annotation

Keyword

3D-structure
Antiviral defense
Cytokine
Disulfide bond
Glycoprotein
Pharmaceutical
Phosphoprotein
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 2** entries
GO Term
extracellular region
extracellular space

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 29 in total

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GO Term
adaptive immune response
T cell activation involved in immune response
B cell activation involved in immune response
humoral immune response
cell surface receptor signaling pathway
response to virus
cytokine-mediated signaling pathway
B cell proliferation
innate immune response
positive regulation of innate immune response

Displaying **all 4** entries
GO Term
chloramphenicol O-acetyltransferase activity
cytokine activity
cytokine receptor binding
type I interferon receptor binding

Annotation information from UniProt.

Sequence

MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSNFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQLQQFQKEDAALTIYEMLQNIFAIFRQDSSSTGWNETIVENLLANVYHQINHLKTVLEEKLEKEDFTRGKLMSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFYFINRLTGYLRN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
101	N-linked (GlcNAc...) asparagine	9342320	G17689DH	UniProt GlyGen
			G17689DH G22310AV	GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 8** entries
Pathway Name	Organism
Evasion by RSV of host interferon responses	Homo sapiens
Factors involved in megakaryocyte development and platelet production	Homo sapiens
Interferon alpha/beta signaling	Homo sapiens
Oxidative Stress Induced Senescence	Homo sapiens
Regulation of IFNA/IFNB signaling	Homo sapiens
SARS-CoV-2 activates/modulates innate and adaptive immune responses	Homo sapiens
TRAF3-dependent IRF activation pathway	Homo sapiens
TRAF6 mediated IRF7 activation	Homo sapiens

Disease

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0080600	COVID-19	Alliance of Genome Resources
DOID:2377	multiple sclerosis	Alliance of Genome Resources
DOID:3526	cerebral infarction	Alliance of Genome Resources
DOID:768	retinoblastoma	Alliance of Genome Resources