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Immunoglobulin heavy constant epsilon

Summary

UniProt ID

P01854

Gene Symbol

IGHE

Organism

Homo sapiens (human)

External Links

GlyConnect

GlyGen

P01854

PubChem

P01854

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin
Immunoglobulin domain
Inflammatory response
Reference proteome
Repeat
Secreted
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 18 in total

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GO Term
inflammatory response
immune response
macrophage differentiation
type 2 immune response
B cell proliferation
macrophage activation
mast cell degranulation
eosinophil degranulation
B cell receptor signaling pathway
type I hypersensitivity

Displaying **all 8** entries
GO Term
extracellular region
extracellular space
plasma membrane
immunoglobulin complex, circulating
IgE immunoglobulin complex
extracellular exosome
IgE B cell receptor complex
blood microparticle

Displaying **all 2** entries
GO Term
immunoglobulin receptor binding
antigen binding

Annotation information from UniProt.

Sequence

ASTQSPSVFPLTRCCKNIPSNATSVTLGCLATGYFPEPVMVTWDTGSLNGTTMTLPATTLTLSGHYATISLLTVSGAWAKQMFTCRVAHTPSSTDWVDNKTFSVCSRDFTPPTVKILQSSCDGGGHFPPTIQLLCLVSGYTPGTINITWLEDGQVMDVDLSTASTTQEGELASTQSELTLSQKHWLSDRTYTCQVTYQGHTFEDSTKKCADSNPRGVSAYLSRPSPFDLFIRKSPTITCLVVDLAPSKGTVNLTWSRASGKPVNHSTRKEEKQRNGTLTVTSTLPVGTRDWIEGETYQCRVTHPHLPRALMRSTTKTSGPRAAPEVYAFATPEWPGSRDKRTLACLIQNFMPEDISVQWLHNEVQLPDARHSTTQPRKTKGSGFFVFSRLEVTRAEWEQKDEFICRAVHEAASPSQTVQRAVSVNPGLAGGSAQSQRAPDRVLCHSGQQQGLPRAAGGSVPHPRCHCGAGRADWPGPPELDVCVEEAEGEAPWTWTGLCIFAALFLLSVSYSAAITLLMVQRFLSATRQGRPQTSLDYTNVLQPHA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
21	N-linked (GlcNAc...) asparagine		G64394MX G57888GL G97268YK G34617SM G68209WQ G11629QQ G79939YZ G31596VW G65219TP G91473PK G25379SA G27102CT G90093AU G24954UD G32246SI G81263BG G08146BT G22310AV G70375MX G02030ZB G05850WN G89098OM G65186XA G72797UR G45495MK G84452RH G61627IG G91636VS G43157UW G79568CQ G03382KH G23863VK G57818FI G10256JP G92129PT G46687AB	UniProt GlyGen GlyConnect
49	N-linked (GlcNAc...) asparagine		G67506FN G64394MX G83295QG G97268YK G34617SM G68209WQ G11629QQ G79939YZ G45883VE G65219TP G91473PK G25379SA G27102CT G90093AU G32246SI G81263BG G08146BT G22310AV G70375MX G02030ZB G05850WN G65186XA G72797UR G45495MK G84452RH G61627IG G91636VS G43157UW G79568CQ G23863VK G57818FI G22140GZ G50045TK	UniProt GlyGen GlyConnect
99	N-linked (GlcNAc...) asparagine		G39595FH G64394MX G83295QG G34617SM G68209WQ G11629QQ G79939YZ G45883VE G65219TP G91473PK G27102CT G90093AU G32246SI G81263BG G08146BT G22310AV G02030ZB G05850WN G65186XA G72797UR G45495MK G84452RH G61627IG G91636VS G43157UW G79568CQ G03382KH G23863VK G57818FI G22140GZ G50045TK	UniProt GlyGen GlyConnect
146	N-linked (GlcNAc...) asparagine		G64394MX G97268YK G34617SM G68209WQ G11629QQ G79939YZ G45883VE G31596VW G65219TP G91473PK G25379SA G27102CT G90093AU G32246SI G81263BG G08146BT G22310AV G70375MX G02030ZB G05850WN G89098OM G45495MK G84452RH G61627IG G91636VS G43157UW G79568CQ G03382KH G23863VK G57818FI G22140GZ G50045TK	UniProt GlyGen GlyConnect
252	N-linked (GlcNAc...) asparagine		G11629QQ G79939YZ G65219TP G91473PK G32246SI G81263BG G08146BT G22310AV G02030ZB G05850WN G72667IM G45495MK G84452RH G82592ZH G61627IG G91636VS G70418MS G50757KG G43157UW G79568CQ G03382KH G23863VK G57818FI G10256JP G92129PT G46687AB	UniProt GlyGen GlyConnect
264	N-linked (GlcNAc...) asparagine		G84452RH G10773YW G61627IG G91636VS G34730YF G03382KH G23863VK G57818FI G10256JP G92129PT G46687AB G82119TF G06110VR G55220VL	UniProt GlyGen GlyConnect
275	N-linked (GlcNAc...) asparagine	10917520	G39617JJ G70101JE G64527OM G66676MI G98940JV G05724UK G48626HI G82020ZR G33609NS G89319AW G26624YG G39188ZX G02815KT G06110VR G54059XR G55220VL G02402FF G66538GV G14669DU G22768VO G03717EM G63628AV	UniProt GlyGen GlyConnect
			G66088HZ G11629QQ G52527GH G14127XU G65219TP G91473PK G81263BG G26403SG G50779LX G08146BT G22310AV G56749GV G59536GA G02030ZB G42358LZ G48414YA G66760KM G67942CH G72667IM G11041DA G12708JQ G30460NZ G53752TA G81413UE G84452RH G20425TQ G29857RC G79809MM G25520XG G61627IG G91636VS G24835MQ G04909DG G06356OH G70101JE G43157UW G79568CQ G03382KH G71013KY G85767HW G23863VK G57818FI G78059CC G64527OM G66676MI G11535IB G23432EQ G10256JP G30159WR G22140GZ G36191CD G50045TK G27919IH G46687AB G58667NI G61937QU G82119TF G82942ZJ G05724UK G82020ZR G10219AA G31936TA G59471TH G75798PH G81295CK G49874UX G56903ZB G80858MF G33609NS G12398HZ G29880MM G68698AP G10471FG G17433EW G39188ZX G80966KZ G23453IV G27993JQ G03127AL G94854LT G06110VR G55220VL G60145BJ G95368PR G47909JD G66538GV	GlyGen GlyConnect GlyConnect GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
FCERI mediated Ca+2 mobilization	Homo sapiens
FCERI mediated MAPK activation	Homo sapiens
FCERI mediated NF-kB activation	Homo sapiens
Fc epsilon receptor (FCERI) signaling	Homo sapiens
Interleukin-4 and Interleukin-13 signaling	Homo sapiens
Role of LAT2/NTAL/LAB on calcium mobilization	Homo sapiens

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

International Collaboration

Acknowledgements