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MIRAGE
Putative HLA class I histocompatibility antigen, alpha chain H
Summary
- UniProt ID
- P01893
- Gene Symbol
- HLA-H HLAH
- Gene ID
- Organism
- Homo sapiens (human)
Annotation
- Keyword
- Cell membrane Disulfide bond Glycoprotein MHC I Proteomics identification Reference proteome Signal Transmembrane helix
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| positive regulation of T cell mediated cytotoxicity | ||
| antigen processing and presentation of endogenous peptide antigen via MHC class Ib | ||
| antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent | ||
| immune response | ||
| immune response |
GO Hierarchy
biological process
immune system process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| Golgi membrane | ||
| Golgi membrane | ||
| obsolete extracellular space |
|
|
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | Reference |
|---|---|---|
| signaling receptor binding | ||
| beta-2-microglobulin binding | ||
| beta-2-microglobulin binding | ||
| peptide antigen binding |
Sequence
MVLMAPRTLLLLLSGALALTQTWARSHSMRYFYTTMSRPGAGEPRFISVGYVDDTQFVRFDSDDASPREEPRAPWMEREGPKYWDRNTQICKAQAQTERENLRIALRYYNQSEGGSHTMQVMYGCDVGPDGPFLRGYEQHAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAARRAEQRRVYLEGEFVEWLRRYLENGKETLQRADPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLTLRWEPSSQPTVPIVGIVAGLVLLVAVVTGAVVAAVMWRKKSSDRKGGSYSQAASSNSAQGSDVSLTA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | Homo sapiens |
| ER-Phagosome pathway | Homo sapiens |
| Endosomal/Vacuolar pathway | Homo sapiens |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | Homo sapiens |
| Interferon alpha/beta signaling | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| Neutrophil degranulation | Homo sapiens |
| SARS-CoV-2 activates/modulates innate and adaptive immune responses | Homo sapiens |
