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H-2 class I histocompatibility antigen, K-B alpha chain

Summary

UniProt ID

P01901

Gene Symbol

H2-K1
H2-K

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003265
GlyGen: P01901
The O-GlcNAc Database: P01901
RaftProt: P01901

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Glycoprotein
MHC I
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
T cell mediated cytotoxicity
positive regulation of T cell mediated cytotoxicity
immune response
antigen processing and presentation of exogenous peptide antigen via MHC class I
defense response to bacterium
negative regulation of neuron projection development
inner ear development
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent

Displaying **all 5** entries
GO Term
extracellular space
external side of plasma membrane
MHC class I protein complex
lumenal side of endoplasmic reticulum membrane
phagocytic vesicle membrane

Displaying **all 5** entries
GO Term
signaling receptor binding
peptide binding
protein-containing complex binding
beta-2-microglobulin binding
peptide antigen binding

Annotation information from UniProt.

Sequence

MVPCTLLLLLAAALAPTQTRAGPHSLRYFVTAVSRPGLGEPRYMEVGYVDDTEFVRFDSDAENPRYEPRARWMEQEGPEYWERETQKAKGNEQSFRVDLRTLLGYYNQSKGGSHTIQVISGCEVGSDGRLLRGYQQYAYDGCDYIALNEDLKTWTAADMAALITKHKWEQAGEAERLRAYLEGTCVEWLRRYLKNGNATLLRTDSPKAHVTHHSRPEDKVTLRCWALGFYPADITLTWQLNGEELIQDMELVETRPAGDGTFQKWASVVVPLGKEQYYTCHVYHQGLPEPLTLRWEPPPSTVSNMATVAVLVVLGAAIVTGAVVAFVMKMRRRNTGGKGGDYALAPGSQTSDLSLPDCKVMVHDPHSLA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
107	N-linked (GlcNAc...) asparagine	19349973 7306483	G72747WU	GlycoProtDB UniProt GlyGen
178				GlyGen
197	N-linked (GlcNAc...) asparagine	7306483	G31852PQ	GlycoProtDB UniProt GlyGen
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Mus musculus
DAP12 interactions	Mus musculus
ER-Phagosome pathway	Mus musculus
Endosomal/Vacuolar pathway	Mus musculus
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Mus musculus
Neutrophil degranulation	Mus musculus