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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
HLA class II histocompatibility antigen, DR alpha chain
Summary
- UniProt ID
- P01903
- Gene Symbol
-
- HLA-DRA
- HLA-DRA1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Host-virus interaction
- Isopeptide bond
- Lysosome
- MHC II
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| Golgi membrane |
| cell surface |
| lysosome |
| plasma membrane |
| MHC class II protein complex |
| endocytic vesicle membrane |
| clathrin-coated endocytic vesicle membrane |
| autolysosome membrane |
| lysosomal membrane |
| ER to Golgi transport vesicle membrane |
| GO Term |
|---|
| MHC class II protein complex binding |
| MHC class II receptor activity |
| polysaccharide binding |
| peptide antigen binding |
| T cell receptor binding |
Sequence
MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGLRKSNAAERRGPL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 103 | N-linked (GlcNAc...) asparagine |
|
||
| 109 |
|
|
||
| 119 |
|
|
||
| 143 | N-linked (GlcNAc...) asparagine |
|
G53075ES
G67164EE
G81637OR
G65414LI
G50856PC
G95046LV
G32788FZ
G39471UU
G05962QB
G54740VA
G70232NH
G37818NZ
G35541EV
G93718GY
G13131HA
G75568BH
G80075MS
G57776ZS
G68490OW
G77669RF
G60834IK
G86880BF
G90382BL
G87123QX
G79666IR
G43669FQ
G45395BF
G59324HL
G14972EH
G43223CG
G49642SA
G78787DI
G76295SF
G04657PL
G27058EU
G51653BI
G08290VR
G70101JE
G01485JJ
G62765YT
G47950XN
G11870QZ
G47644PP
G31852PQ
G41247ZX
G92275SC
G89827JR
G11101UV
G27947YN
G40926MX
G22625SJ
G00912UN
G87661QW
G15664MX
G83460ZZ
G23984SE
G10773YW
G49018RC
G72747WU
G70619PT
G59626AS
G46503DX
G01650EU
G80920RR
G02886BB
G90659AW
G59924QI
G37399XV
G82463GQ
G64527OM
G62894KT
G10486CT
G28541PG
G18647XP
G95865ZB
G05724UK
G39446WN
G39188ZX
G25637MV
G57776ZU
G02815KT
G06110VR
G92050GC
G14669DU
G28681TP
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downstream TCR signaling | Homo sapiens |
| Generation of second messenger molecules | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| MHC class II antigen presentation | Homo sapiens |
| PD-1 signaling | Homo sapiens |
| Phosphorylation of CD3 and TCR zeta chains | Homo sapiens |
| Translocation of ZAP-70 to Immunological synapse | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
