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Alpha-crystallin A chain

Summary

UniProt ID: P02502
Gene Symbol: CRYAA
Gene ID
Organism: Osphranter rufus (red kangaroo)

External Links

PubChem: P02502
Re-Glyco: P02502

Annotation

Keyword: Acetylation Chaperone Cytoplasm Direct protein sequencing Eye lens protein Glycoprotein Metal-binding Methylation Nucleus Phosphoprotein Zinc

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	Reference
lens development in camera-type eye	IEA	GO_REF
response to heat	IEA	GO_REF
protein refolding	IEA	GO_REF
negative regulation of apoptotic process	IEA	GO_REF

GO Hierarchy

biological process

cellular process [inference]

protein folding [inference]

protein refolding

developmental process [inference]

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

lens development in camera-type eye

response to stimulus [inference]

response to stress [inference]

response to heat

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

Displaying **all 4** entries
GO Term	Evidence Code	Reference
nucleus	ISS	GO_REF
nucleus	IEA	GO_REF GO_REF
cytoplasm	ISS	GO_REF
cytoplasm	IEA	GO_REF GO_REF GO_REF

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	Reference
structural constituent of eye lens	IEA	GO_REF
metal ion binding
obsolete unfolded protein binding

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of eye lens

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from UniProt.

Annotation information from UniProt.

Sequence

MDITIQHPWFKRALGSLYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLESGISEVRSDRDKFVIFLDVKHFSPEDLTVKVLDDFVEIHGKHSERQDDHGYISREFHRRYRLPSNVDQSAISCSLSADGMLTFSGPKIHSDMDASHSDRSIPVSREEKPTLAPSS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites