GlyCosmos Portal

Submissions

Apolipoprotein A-I

Summary

UniProt ID

P02647

Gene Symbol

APOA1

Organism

Homo sapiens (human)

External Links

GlyGen: P02647
PubChem: P02647
The Human Metabolome Database: HMDBP01620
RaftProt: P02647

Annotation

Keyword

3D-structure
Amyloid
Amyloidosis
Atherosclerosis
Cholesterol metabolism
Direct protein sequencing
Disease variant
Glycation
HDL
Lipid transport
Neuropathy
Oxidation
Palmitate
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal

Gene Ontology (GO)

Displaying entries **11 - 20** of 48 in total

« First

‹ Prev

1

2

3

4

5

Next ›

Last »
GO Term
blood vessel endothelial cell migration
positive regulation of phagocytosis
positive regulation of hydrolase activity
protein stabilization
positive regulation of stress fiber assembly
acylglycerol homeostasis
phospholipid homeostasis
negative regulation of cell adhesion molecule production
reverse cholesterol transport
cholesterol biosynthetic process

Displaying entries **1 - 10** of 19 in total

1

2

Next ›

Last »
GO Term
cytosol
early endosome
endoplasmic reticulum lumen
very-low-density lipoprotein particle
low-density lipoprotein particle
high-density lipoprotein particle
spherical high-density lipoprotein particle
chylomicron
blood microparticle
extracellular region

Displaying entries **1 - 10** of 15 in total

1

2

Next ›

Last »
GO Term
signaling receptor binding
enzyme binding
phosphatidylcholine-sterol O-acyltransferase activator activity
cholesterol binding
heat shock protein binding
cholesterol transfer activity
identical protein binding
protein homodimerization activity
chemorepellent activity
amyloid-beta binding

Annotation information from UniProt.

Sequence

MKAAVLTLAVLFLTGSQARHFWQQDEPPQSPWDRVKDLATVYVDVLKDSGRDYVSQFEGSALGKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPALEDLRQGLLPVLESFKVSFLSALEEYTKKLNTQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
220			G57321FI	GlyGen
221			G57321FI	GlyGen
228			G57321FI	GlyGen
263	N-linked (Glc) (glycation) lysine	8261628		UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 17** of 17 in total

« First

‹ Prev

1

2
Pathway Name	Organism
Platelet degranulation	Homo sapiens
Post-translational protein phosphorylation	Homo sapiens
Regulation of IGF Activity by IGFBP	Homo sapiens
Retinoid metabolism and transport	Homo sapiens
Scavenging by Class A Receptors	Homo sapiens
Scavenging by Class B Receptors	Homo sapiens
Scavenging of heme from plasma	Homo sapiens