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MIRAGE
Plasma kallikrein

Summary
UniProt ID
P03952
Gene Symbol
  • KLK3
  • KLKB1
Gene ID
3818
Organism
Homo sapiens (human)
GlycoProtDB
GPDB0011343
GlyConnect
GlyGen
P03952
PubChem
P03952
The Human Metabolome Database
HMDBP02080
Re-Glyco
P03952
Annotation
Keyword
  • 3D-structure
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Fibrinolysis
  • Glycoprotein
  • Inflammatory response
  • Reference proteome
  • Repeat
  • Secreted
  • Serine protease
  • Signal
  • Zymogen
Gene Ontology (GO)
Displaying all 4 entries
GO Term
extracellular region
extracellular space
plasma membrane
extracellular exosome
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
serine-type endopeptidase activity
Annotation information from UniProt.
Sequence
MILFKQATYFISLFATVSCGCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLFSFLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVDMRGVNFNVSKVSSVEECQKRCTSNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIKVLSNVESGFSLKPCALSEIGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFFTFYTNVWKIESQRNVCLLKTSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGVDFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 10 entries
Position Description PubMed ID GlyTouCan ID Source
127 N-linked (GlcNAc...) asparagine
164
254
265
308 N-linked (GlcNAc...) asparagine
316
374
396 N-linked (GlcNAc...) asparagine
453 N-linked (GlcNAc...) asparagine
494 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 4 entries
Pathway Name Organism
Activation of Matrix Metalloproteinases Homo sapiens
Defective SERPING1 causes hereditary angioedema Homo sapiens
Defective factor XII causes hereditary angioedema Homo sapiens
Intrinsic Pathway of Fibrin Clot Formation Homo sapiens
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:0080162 lupus nephritis
DOID:9074 systemic lupus erythematosus
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025