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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Major prion protein
Summary
- UniProt ID
- P04156
- Gene Symbol
-
- PRNP
- ALTPRP
- PRIP
- PRP
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011355
- GlyConnect
- GlyGen
- P04156
- PubChem
- P04156
- The Human Metabolome Database
- HMDBP02352
- The O-GlcNAc Database
- P04156
- RaftProt
- P04156
Annotation
- Keyword
-
- 3D-structure
- Alternative initiation
- Amyloidosis
- Cell membrane
- Copper
- Direct protein sequencing
- Disease variant
- Disulfide bond
- GPI-anchor
- Golgi apparatus
- Growth arrest
- Metal-binding
- Prion
- Reference proteome
- Repeat
- Signal
- Zinc
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| Golgi apparatus |
| plasma membrane |
| nuclear membrane |
| terminal bouton |
| intracellular membrane-bounded organelle |
| dendrite |
| membrane raft |
| extracellular exosome |
| postsynapse |
Sequence
MEHWGQPIPGAGQPWRQPLPTSGRWWLGAASWWWLGAASWWWLGAAPWWWLGTASWWWLGSRRWHPQSVEQAE
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 82 |
|
|||
| 95 |
|
|||
| 181 | N-linked (GlcNAc...) asparagine | |||
| 186 |
|
|||
| 192 |
|
|||
| 197 | N-linked (GlcNAc...) asparagine | |||
|
|
G57321FI
G03636KD
G68490OW
G98611JV
G83460ZZ
G80920RR
G62765YT
G10256JP
G88725PI
G46687AB
G59937CP
G25987BV
G49874UX
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Insertion of tail-anchored proteins into the endoplasmic reticulum membrane | Homo sapiens |
| NCAM1 interactions | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050433 | fatal familial insomnia | |
| DOID:0050452 | mevalonic aciduria | |
| DOID:0050539 | Charcot-Marie-Tooth disease type 2 | |
| DOID:0050569 | Seckel syndrome | |
| DOID:0050572 | cone-rod dystrophy | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050635 | alternating hemiplegia of childhood | |
| DOID:0050639 | primary cutaneous amyloidosis | |
| DOID:0050753 | cerebellar ataxia | |
| DOID:0050759 | myotonic dystrophy type 2 |
