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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Complement factor B
Summary
- UniProt ID
- P04186
- Gene Symbol
-
- Cfb
- Bf
- H2-Bf
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003272
- GlyGen
- P04186
- PubChem
- P04186
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Complement alternate pathway
- Disulfide bond
- Glycoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Sushi
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| proteolysis |
| complement activation |
| response to bacterium |
| B cell proliferation |
| complement activation, alternative pathway |
| GO Term |
|---|
| extracellular region |
| GO Term |
|---|
| serine-type endopeptidase activity |
Sequence
MESPQLCLVLLVLGFSSGGVSATPVLEARPQVSCSLEGVEIKGGSFQLLQGGQALEYLCPSGFYPYPVQTRTCRSTGSWSDLQTRDQKIVQKAECRAIRCPRPQDFENGEFWPRSPFYNLSDQISFQCYDGYVLRGSANRTCQENGRWDGQTAICDDGAGYCPNPGIPIGTRKVGSQYRLEDIVTYHCSRGLVLRGSQKRKCQEGGSWSGTEPSCQDSFMYDSPQEVAEAFLSSLTETIEGADAEDGHSPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGSSNFTGAKRCLTNLIEKVASYGVRPRYGLLTYATVPKVLVRVSDERSSDADWVTEKLNQISYEDHKLKSGTNTKRALQAVYSMMSWAGDAPPEGWNRTRHVIIIMTDGLHNMGGNPVTVIQDIRALLDIGRDPKNPREDYLDVYVFGVGPLVDSVNINALASKKDNEHHVFKVKDMEDLENVFYQMIDETKSLSLCGMVWEHKKGNDYHKQPWQAKISVTRPLKGHETCMGAVVSEYFVLTAAHCFMVDDQKHSIKVSVGGQRRDLEIEEVLFHPKYNINGKKAEGIPEFYDYDVALVKLKNKLKYGQTLRPICLPCTEGTTRALRLPQTATCKQHKEQLLPVKDVKALFVSEQGKSLTRKEVYIKNGDKKASCERDATKAQGYEKVKDASEVVTPRFLCTGGVDPYADPNTCKGDSGGPLIVHKRSRFIQVGVISWGVVDVCRDQRRQQLVPSYARDFHINLFQVLPWLKDKLKDEDLGFL
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 119 | N-linked (GlcNAc...) asparagine |
|
||
| 139 | N-linked (GlcNAc...) asparagine |
|
||
| 282 | N-linked (GlcNAc...) asparagine |
|
||
| 375 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of C3 and C5 | Mus musculus |
| Alternative complement activation | Mus musculus |
| Regulation of Complement cascade | Mus musculus |
