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Pancreatic alpha-amylase

Summary

UniProt ID

P04746

Gene Symbol

AMY2A

Organism

Homo sapiens (human)

External Links

GlyGen: P04746
PubChem: P04746
The Human Metabolome Database: HMDBP02084

Annotation

Keyword

3D-structure
Alternative splicing
Calcium
Carbohydrate metabolism
Chloride
Disulfide bond
Glycoprotein
Glycosidase
Metal-binding
Pyrrolidone carboxylic acid
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
carbohydrate metabolic process
carbohydrate catabolic process
polysaccharide digestion

Displaying **all 3** entries
GO Term
extracellular region
extracellular space
extracellular exosome

Displaying **all 3** entries
GO Term
calcium ion binding
chloride ion binding
alpha-amylase activity

Annotation information from UniProt.

Sequence

MKFFLLLFTIGFCWAQYSPNTQQGRTSIVHLFEWRWVDIALECERYLAPKGFGGVQVSPPNENVAIYNPFRPWWERYQPVSYKLCTRSGNEDEFRNMVTRCNNVGVRIYVDAVINHMCGNAVSAGTSSTCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLTGLLDLALEKDYVRSKIAEYMNHLIDIGVAGFRLDASKHMWPGDIKAILDKLHNLNSNWFPAGSKPFIYQEVIDLGGEPIKSSDYFGNGRVTEFKYGAKLGTVIRKWNGEKMSYLKNWGEGWGFVPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKMAVGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWRQIRNMVIFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWSFSLTLQTGLPAGTYCDVISGDKINGNCTGIKIYVSDDGKAHFSISNSAEDPFIAIHAESKL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
212				GlyGen
476	N-linked (GlcNAc...) asparagine	10091666 10769135 11772019		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying 1 entry
Pathway Name	Organism
Digestion of dietary carbohydrate	Homo sapiens

Human Protein Atlas

ENSG00000243480

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Disease

Displaying entries **1 - 10** of 36 in total

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Last »
DO ID	Disease Name	Source
DOID:0040091	autoimmune pancreatitis	DisGeNET
DOID:0110741	type 1 diabetes mellitus 2	DisGeNET
DOID:0110742	type 1 diabetes mellitus 3	DisGeNET
DOID:0110743	type 1 diabetes mellitus 4	DisGeNET
DOID:0110744	type 1 diabetes mellitus 5	DisGeNET
DOID:0110745	type 1 diabetes mellitus 6	DisGeNET
DOID:0110746	type 1 diabetes mellitus 7	DisGeNET
DOID:0110747	type 1 diabetes mellitus 8	DisGeNET
DOID:0110748	obsolete type 1 diabetes mellitus 9	DisGeNET
DOID:0110749	type 1 diabetes mellitus 10	DisGeNET

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements