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Plasma protease C1 inhibitor

Summary

UniProt ID

P05155

Gene Symbol

SERPING1
C1IN
C1NH

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011388

GlyConnect

GlyGen

P05155

PubChem

P05155

RaftProt

P05155

Annotation

Keyword

3D-structure
Alternative splicing
Complement pathway
Direct protein sequencing
Disease variant
Disulfide bond
Fibrinolysis
Glycoprotein
Reference proteome
Repeat
Secreted
Serine protease inhibitor
Signal

Gene Ontology (GO)

Displaying **all 6** entries
GO Term
negative regulation of complement activation, lectin pathway
complement activation, classical pathway
blood coagulation
blood circulation
fibrinolysis
innate immune response

Displaying **all 7** entries
GO Term
platelet alpha granule lumen
extracellular exosome
blood microparticle
endoplasmic reticulum lumen
extracellular region
extracellular space
collagen-containing extracellular matrix

Displaying 1 entry
GO Term
serine-type endopeptidase inhibitor activity

Annotation information from UniProt.

Sequence

MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPILEVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDPRA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **21 - 30** of 30 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
103				GlyGen
113			G53434XO	GlyGen
115			G43417UB	GlyGen
118			G53434XO G43417UB	GlyGen
119			G43417UB	GlyGen
238	N-linked (GlcNAc...) (complex) asparagine	14760718 16335952 17488724 19139490 19159218 3756141	G35107SO G10019LZ G43089EG G38663NM G70232NH G70888PK G06247RL G93718GY G80075MS G11629QQ G57776ZS G68490OW G77669RF G86880BF G27947YN G90382BL G80479JV G85282JO G20528HD G04854VP G94470IW G87123QX G79666IR G92135MA G34989PA G45395BF G07246CJ G10819WX G40926MX G14972EH G02030ZB G12580WI G43223CG G26330YA G10846ZT G40574BA G08918WF G75983OB G00912UN G42358LZ G48414YA G27915IV G92551JA G70441OD G83646BJ G76295SF G46691LC G27126ED G08293MJ G27058EU G45495MK G84452RH G83460ZZ G41071NU G85740DB G91636VS G07755XJ G35253PZ G70619PT G06356OH G59626AS G08290VR G01650EU G70101JE G80920RR G42124LM G90659AW G45504EY G64409MC G62765YT G64527OM G47644PP G10486CT G05049YU G95865ZB G31852PQ G11314AS G41247ZX G57776ZU G36379GD G02815KT G57317CE G92050GC G92275SC G28681TP G89045VA	GlycoProtDB UniProt GlyGen GlyConnect
253	N-linked (GlcNAc...) (complex) asparagine	12754519 14760718 16335952 19139490 19159218 3756141	G87399DK G53075ES G18804KX G30221QT G81637OR G82443XX G32788FZ G18589KA G55412XP G56518TU G05962QB G30740WO G15169WU G70232NH G94917XT G55132BD G69521XL G70888PK G92081HT G03644CB G33791AF G06247RL G47518TP G35541EV G93718GY G80075MS G11629QQ G57776ZS G68490OW G99668VU G77669RF G86795LJ G86880BF G27947YN G52527GH G90382BL G56784JY G04854VP G94470IW G87123QX G79666IR G98611JV G34989PA G47748JZ G40834TG G86500WE G02528FI G43669FQ G51413EV G22310AV G45395BF G88374WZ G59324HL G07246CJ G40926MX G14972EH G43223CG G31986NC G26330YA G10846ZT G40574BA G82830MN G08918WF G71146HJ G75983OB G00912UN G42358LZ G48414YA G58087IP G11911BT G46691LC G27126ED G04657PL G27058EU G84452RH G51653BI G83460ZZ G41071NU G49018RC G72747WU G70619PT G06356OH G59626AS G80920RR G90659AW G29299MO G37399XV G62765YT G47644PP G10486CT G95865ZB G31852PQ G41247ZX G57776ZU G02815KT G92275SC G28681TP G54010QB	GlycoProtDB UniProt GlyGen GlyConnect
272				UniProt GlyGen
326				GlyGen
352	N-linked (GlcNAc...) (complex) asparagine	14760718 16335952 19139490 19159218 19838169 3756141	G01521EA G67164EE G05962QB G06247RL G80075MS G11629QQ G57776ZS G77669RF G27947YN G52527GH G37692EO G04854VP G94470IW G43669FQ G45395BF G88374WZ G59324HL G20706XG G14972EH G43223CG G49642SA G26330YA G10846ZT G40574BA G82830MN G08918WF G47737VJ G00912UN G48414YA G11911BT G92551JA G61256FT G15664MX G34029GR G08293MJ G27058EU G72747WU G60923RB G70619PT G06356OH G59626AS G80920RR G42124LM G90659AW G62765YT G10486CT G22140GZ G50045TK G95865ZB G98129XB	GlycoProtDB UniProt GlyGen GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
Defective SERPING1 causes hereditary angioedema	Homo sapiens
Intrinsic Pathway of Fibrin Clot Formation	Homo sapiens
Platelet degranulation	Homo sapiens
Regulation of Complement cascade	Homo sapiens

Human Protein Atlas

ENSG00000149131

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements