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Mast/stem cell growth factor receptor Kit

Summary

UniProt ID

P05532

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB: GPDB0003283
GlyGen: P05532
PubChem: P05532
The O-GlcNAc Database: P05532

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cell membrane
Cytoplasm
Disease variant
Disulfide bond
Glycoprotein
Immunoglobulin domain
Magnesium
Metal-binding
Phosphoprotein
Proto-oncogene
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **61 - 70** of 72 in total

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GO Term
positive regulation of MAPK cascade
positive regulation of tyrosine phosphorylation of STAT protein
positive regulation of Notch signaling pathway
melanocyte adhesion
positive regulation of pyloric antrum smooth muscle contraction
ovarian follicle development
hematopoietic progenitor cell differentiation
myeloid progenitor cell differentiation
lymphoid progenitor cell differentiation
immature B cell differentiation

Displaying **all 9** entries
GO Term
acrosomal vesicle
extracellular space
fibrillar center
external side of plasma membrane
cytoplasmic side of plasma membrane
cell surface
plasma membrane
cell-cell junction
receptor complex

Displaying **all 10** entries
GO Term
stem cell factor receptor activity
ATP binding
growth factor binding
SH2 domain binding
cytokine binding
metal ion binding
protein homodimerization activity
protease binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity

Annotation information from UniProt.

Sequence

MRGARGAWDLLCVLLVLLRGQTATSQPSASPGEPSPPSIHPAQSELIVEAGDTLSLTCIDPDFVRWTFKTYFNEMVENKKNEWIQEKAEATRTGTYTCSNSNGLTSSIYVFVRDPAKLFLVGLPLFGKEDSDALVRCPLTDPQVSNYSLIECDGKSLPTDLTFVPNPKAGITIKNVKRAYHRLCVRCAAQRDGTWLHSDKFTLKVRAAIKAIPVVSVPETSHLLKKGDTFTVVCTIKDVSTSVNSMWLKMNPQPQHIAQVKHNSWHRGDFNYERQETLTISSARVDDSGVFMCYANNTFGSANVTTTLKVVEKGFINISPVKNTTVFVTDGENVDLVVEYEAYPKPEHQQWIYMNRTSANKGKDYVKSDNKSNIRYVNQLRLTRLKGTEGGTYTFLVSNSDASASVTFNVYVNTKPEILTYDRLINGMLQCVAEGFPEPTIDWYFCTGAEQRCTTPVSPVDVQVQNVSVSPFGKLVVQSSIDSSVFRHNGTVECKASNDVGKSSAFFNFAFKGNNKEQIQAHTLFTPLLIGFVVAAGAMGIIVMVLTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTVGGPTLVITEYCCYGDLLNFLRRKRDSFIFSKQEEQAEAALYKNLLHSTEPSCDSSNEYMDMKPGVSYVVPTKTDKRRSARIDSYIERDVTPAIMEDDELALDLDDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIRNDSNYVVKGNARLPVKWMAPESIFSCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMVSPEHAPAEMYDVMKTCWDADPLKRPTFKQVVQLIEKQISDSTKHIYSNLANCNPNPENPVVVDHSVRVNSVGSSASSTQPLLVHEDA

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
146	N-linked (GlcNAc...) asparagine		G86182NS	GlycoProtDB UniProt GlyGen
296	N-linked (GlcNAc...) asparagine	17255936		UniProt GlyGen
303	N-linked (GlcNAc...) asparagine	17255936	G37412TK	UniProt GlyGen
323	N-linked (GlcNAc...) asparagine			UniProt GlyGen
355	N-linked (GlcNAc...) asparagine			UniProt GlyGen
370	N-linked (GlcNAc...) asparagine			UniProt GlyGen
466	N-linked (GlcNAc...) asparagine		G43223CG	UniProt GlyGen
489	N-linked (GlcNAc...) asparagine		G02815KT	GlycoProtDB UniProt GlyGen
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
PI3K/AKT Signaling	Mus musculus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Mus musculus
RAF/MAP kinase cascade	Mus musculus
Regulation of KIT signaling	Mus musculus
Signaling by SCF-KIT	Mus musculus
Transcriptional and post-translational regulation of MITF-M expression and activity	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements